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82005-44-5

82005-44-5 Structure

82005-44-5 Structure
IdentificationBack Directory
[Name]

OLEIC-1-13C ACID 99 ATOM % 13C
[CAS]

82005-44-5
[Synonyms]

atom%13c
Oleic Acid-13C
(Z)-9-Octadecenoic Acid-13C
9Δ-cis-Octadecenoic Acid-13C
OLEIC-1-13C ACID 99 ATOM % 13C
[Molecular Formula]

C18H34O2
[MDL Number]

MFCD01073865
[MOL File]

82005-44-5.mol
[Molecular Weight]

283.47
Chemical PropertiesBack Directory
[Melting point ]

13.4 °C(lit.)
[Boiling point ]

192-195 °C1.2 mm Hg(lit.)
[density ]

0.893 g/mL at 25 °C
[refractive index ]

n20/D 1.4595(lit.)
[Fp ]

>230 °F(lit.)
[storage temp. ]

-20°C
[solubility ]

Ethanol: 1.5 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid (Item Nos. 90260 | 24659) by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue. It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets. Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 μg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 μM, similar to arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607). Oleic acid (60 μM) induces release of intracellular calcium in human platelets. In vivo, oleic acid increases TNF-α, IL-8, IL-6, and IL-1β production, neutrophil accumulation, and apoptotic and necrotic cell death in mouse lung and has been used to induce lung injury in a mouse model of acute respiratory distress syndrome (ARDS).
[Uses]

Labelled Oleic acid. Obtained by the hydrolysis of various animal and vegetable fats and oils.
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