ChemicalBook--->CAS DataBase List--->82801-73-8

82801-73-8

82801-73-8 Structure

82801-73-8 Structure
IdentificationBack Directory
[Name]

ARG-LYS-ARG-ALA-ARG-LYS-GLU
[CAS]

82801-73-8
[Synonyms]

RKRARKE
PKG INHIBITOR
PKG Inhibitor,RKRARKE
PROTEIN KINASE G INHIBITOR
ARG-LYS-ARG-ALA-ARG-LYS-GLU
[ALA32]-HISTONE H2B (29-35)
OUKSKNTVYYVIMZ-DUJSLOSMSA-N
Alg-Lys-Arg-Ala-Arg-Lys-Glu
H-ARG-LYS-ARG-ALA-ARG-LYS-GLU-OH
ARG-LYS-ARG-ALA-ARG-LYS-GLU: RKRARKE
CGMP DEPENDENT KINASE INHIBITOR PEPTIDE
cGMP-Dependent Protein Kinase Inhibitor Peptide
arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid
L-Glutamic acid, L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl-
[Molecular Formula]

C38H74N18O10
[MDL Number]

MFCD00080098
[MOL File]

82801-73-8.mol
[Molecular Weight]

943.11
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Solid
[Water Solubility ]

Soluble in water at 1mg/ml
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 μM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells.
[Uses]

A reversible substrate competitive inhibitor for protein kinase G. The sequence corresponds to a non-phosphorylatable analog of histone H2B.
[storage]

Store at -20°C
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