Identification | Back Directory | [Name]
CTC | [CAS]
90217-02-0 | [Synonyms]
CTC Ctc (biological Stain) Cyanotolyl Tetrazolium, Ctc CYANODITOLYL TETRAZOLIUM CHLORIDE CYANOTOLYL TETRAZOLIUM CHLORIDE (CTC) 5-CYANO-2,3-DITOLYL TETRAZOLIUM CHLORIDE CTC 5-Cyano-2,3-ditolyl tetrazolium chloride 5-CYANO-2,3-DI-(P-TOLYL)TETRAZOLIUM CHLORIDE 5-Cyano-2,3-bis(4-methylphenyl)tetrazolium chloride 5-CYANO-2,3-BIS(4-METHYLPHENYL)-2H-TETRAZOLIUM CHLORIDE 2h-tetrazolium, 5-cyano-2,3-bis(4methylphenyl)-, Chloride 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride, ≥85% (HPLC) | [Molecular Formula]
C16H14ClN5 | [MDL Number]
MFCD00467521 | [MOL File]
90217-02-0.mol | [Molecular Weight]
311.77 |
Chemical Properties | Back Directory | [Melting point ]
225 ℃ | [storage temp. ]
2-8°C | [solubility ]
Soluble in water | [form ]
powder | [color ]
Off-white | [λmax]
450nm (of formazan) | [BRN ]
8954451 | [Biological Applications]
NADPH-cytochrome P 450 reductase activity assays; detecting gamma-hydroxybutyric acid (GHB),metabolic activity,microorganisms; localizing glucose-6-phosphate dehydrogenase activity; monitoring respiratory activity; treating cancer |
Hazard Information | Back Directory | [Description]
5-Cyano-2,3-di-(p-tolyl)tetrazolium (chloride) is a redox-sensitive tetrazolium salt used primarily to detect metabolic activity in microorganisms. This membrane-permeable indicator is readily taken up by living cells and reduced by respiratory activity to produce a red fluorescent, water-insoluble formazan crystal (absorption maximum at 450 nm). While the oxidized salt is non-fluorescent, the reduced formazan can be evaluated using a standard rhodamine filter set (excitation: 510-560 nm; emission > 590 nm), although optimum excitation requires a blue 420 nm excitation filter. For flow cytometry, a 480 nm excitation laser combined with detection in the red region is suitable. | [Uses]
5-Cyano-2,3-di-p-tolyltetrazolium Chloride is a monotetrazolium redox dye that is used as a vital stain for actively respiring bacteria. Redox dye producing a fluorescent formazan (only in solid state) upon reduction; used as cellular indicator of respiratory activity in cells. | [Uses]
Redox dye producing a fluorescent formazan (only in solid state) upon reduction. It is used as cellular indicator of respiratory activity in cells, especiall for tracking P450 activity. |
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