ChemicalBook--->CAS DataBase List--->97501-92-3

97501-92-3

97501-92-3 Structure

97501-92-3 Structure
IdentificationBack Directory
[Name]

CHYMASE
[CAS]

97501-92-3
[Synonyms]

chymase human
Chymase from Human, Recombinant
[MDL Number]

MFCD00132173
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
Safety DataBack Directory
[Hazard Codes ]

B
[WGK Germany ]

1
Hazard InformationBack Directory
[Uses]

Human chymase has been used in a study to assess the effects of Panax notoginseng flower extract on the TGF-β/Smad signal transduction pathway in heart remodeling. Human chymase has also been used in a study to investigate the blood glucose level and survival in streptozotocin-treated human chymase transgenic mice.
[Biochem/physiol Actions]

The enzyme rapidly converts angiotensin I to angiotensin II. Optimum pH for the enzyme activity is between 7.5 and 9.0. Enzyme activity is inhibited by soybean trypsin inhibitor, phenylmethylsulfonyl fluoride and chymostatin.
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