532-11-6
532-11-6 结构式
基本信息
胆维他
茴三硫
3-对甲氧苯基三硫酮
5-(对-甲氧基苯基)-1,2-二硫环戊烯-3-硫酮
茴香脑三硫酮
5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione
ANETHOLE TRITHIONE
3-(p-anisy)trithione
3-(p-Methoxyphenyl)trithione
3-(p-Methoxyphenyl)-trithione
3H-1,2-Dithiole-3-thione, 5-(p-methoxyphenyl)-
5-(4-methoxyphenyl)-3h-2-dithiole-3-thione
5-(p-Methoxyphenyl)-1,2-dithiocyclopenten-3-thione
5-(p-Methoxyphenyl)-3H-1,2-dithiole-3-thione
5-(p-methoxyphenyl)-3h-2-dithiole-3-thione
AnetholTrithione
Felviten
Heporal
Mucinol
SKF 1717
skf1717
Sufralem
Sulfarlem
Sulfogal
物理化学性质
制备方法
532-11-6(安全特性,毒性,储运)
常见问题列表
茴三硫又称胆维他、茴香脑三硫酮，属于分泌性利胆药，能明显增强肝脏谷胱甘肽水平，显著增强谷氨酰半胱氨酸合成酶、谷胱甘肽还原酶和谷胱甘肽硫转移酶活性，降低谷胱甘肽过氧化酶活性，增强肝细胞活力，使胆汁分泌增多。不增加肝脏负担，可降低肝脏门脉压力，消除肝炎病灶的肝充血等症状，促进肝细胞活化，有助于肝功能的改善和恢复。能保护肝脏免受肝毒性物质的损害。能显著增加毒蕈碱样乙酰胆碱受体数，促进唾液分泌。具有胃肠道M受体和β2受体调节作用，促进胃肠蠕动和肠管内气体排出。适用于治疗胆囊炎、胆管炎、胆石症以及高胆固醇血症; 可用于急、慢性肝炎，初期肝硬化的治疗;或用于消除腹胀、便秘、口臭、恶心、闷痛等消化不适。
以上信息由Chemicalbook彤彤编辑整理。
Anethole trithione, a slow-releasing H 2 S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia.
Chronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased.