6138-41-6
6138-41-6 结构式
基本信息
盐酸胡芦巴碱
葫芦巴碱盐酸盐
盐酸葫芦巴碱
N-METHYLNICOTINIC ACID BETAINE HYDROCHLORIDE
TIMTEC-BB SBB000182
TRIGONELLINE HCL
TRIGONELLINE HYDROCHLORIDE
TRIGONELLIN HYDROCHLORIDE
3-carboxy-1-methylpyridinium chloride
Trigonelline chloride
EINECS 228-119-5
1-Methylpyridinium-3-carboxylate hydrochloride, N-Methylnicotinic acid betaine hydrochloride
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-N0415 | 盐酸胡芦巴碱 Trigonelline chloride | 6138-41-6 | 100mg | 500元 |
| 2024/01/25 | HY-N0415 | 盐酸胡芦巴碱 Trigonelline chloride | 6138-41-6 | 10mM * 1mLin DMSO | 550元 |
| 2024/01/25 | HY-N0415 | 盐酸胡芦巴碱 Trigonelline chloride | 6138-41-6 | 500mg | 800元 |
常见问题列表
It is found that Trigonelline chloride (TG) significantly rescues the morphology of the H9c2 cells. Treatment of cells with Trigonelline chloride attenuates H 2 O 2 induced cell deaths and improves the antioxidant activity. In addition, Trigonelline chloride regulates the apoptotic gene caspase-3, caspase-9 and anti-apoptotic gene Bcl-2, Bcl-XL during H 2 O 2 induced oxidative stress in H9c2 cells. For evident, flow cytometer results also confirm that Trigonelline chloride significantly reduces the H 2 O 2 induced necrosis and apoptosis in H9c2 cells. However, further increment of Trigonelline chloride concentration against H 2 O 2 can induce the necrosis and apoptosis along with H 2 O 2 .
Trigonelline chloride decreases bone mineralization and tends to worsen bone mechanical properties in streptozotocin-induced diabetic rats. In nicotinamide/streptozotocin-treated rats, Trigonelline chloride significantly increases bone mineral density (BMD) and tends to improve cancellous bone strength. Trigonelline chloride differentially affects the skeletal system of rats with streptozotocin-induced metabolic disorders, intensifying the osteoporotic changes in streptozotocin-treated rats and favorably affecting bones in the non-hyperglycemic (nicotinamide/streptozotocin-treated) rats.