芍药甙元酮
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- CAS号:
- 80454-42-8
- 英文名:
- paeoniflorigenone
- 英文别名:
- paeoniflorigenone;2,5-Methano-1,3-benzodioxol-6(3aH)-one, 8-[(benzoyloxy)methyl]tetrahydro-3a-hydroxy-7a-methyl-, (2S,3aR,5R,7aS,8S)-
- 中文名:
- 芍药甙元酮
- 中文别名:
- 芍药吉酮;芍药苷元酮;芍药甙元酮
- CBNumber:
- CB11336545
- 分子式:
- C17H18O6
- 分子量:
- 318.32
- MOL File:
- 80454-42-8.mol
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芍药甙元酮化学性质
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沸点:
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481.1±45.0 °C(Predicted)
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密度:
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1.396±0.06 g/cm3(Predicted)
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储存条件:
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4°C, protect from light
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溶解度:
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Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
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形态:
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Powder
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酸度系数(pKa):
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11.81±0.60(Predicted)
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芍药甙元酮性质、用途与生产工艺
Paeoniflorigenone 是从牡丹皮中提取的一种有效成分，具有选择性诱导肿瘤细胞凋亡 (apoptosis) 和抗增殖作用。
Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines.
Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells.
Cell Proliferation Assay
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Cell Line:
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TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells
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Concentration:
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0-30 μM
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Incubation Time:
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0-72 hours
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Result:
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Significantly decreased the cell proliferation of tumor cell lines and inhibited the proliferation of normal cell lines.
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Apoptosis Analysis
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Cell Line:
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TIG-1 and 3T3-L1 (normal cells), HL60, Jurkat, and HeLa cells (tumor cells)
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Concentration:
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0, 1, 3, 10, 30 μM
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Incubation Time:
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24 and 72 hours
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Result:
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Induced DNA fragmentation in three tumor cell lines, but not in two normal cell lines.
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芍药甙元酮
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-N3119 | 芍药甙元酮
Paeoniflorigenone | 80454-42-8 | 1mg | 8000元 |
80454-42-8, 芍药甙元酮 相关搜索:
- 标准品，对照品
- 其它萜类
- 对照品
- 中药对照品
- 植物提取物
- 标准品
- 芍药吉酮
- 芍药苷元酮
- 芍药甙元酮
- 80454-42-8
- 2,5-Methano-1,3-benzodioxol-6(3aH)-one, 8-[(benzoyloxy)methyl]tetrahydro-3a-hydroxy-7a-methyl-, (2S,3aR,5R,7aS,8S)-
- paeoniflorigenone