芍药甙元酮
芍药甙元酮 性质
| 沸点 | 481.1±45.0 °C(Predicted) |
|---|---|
| 密度 | 1.396±0.06 g/cm3(Predicted) |
| 储存条件 | 4°C, protect from light |
| 溶解度 | 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。 |
| 形态 | 粉末 |
| 酸度系数(pKa) | 11.81±0.60(Predicted) |
Paeoniflorigenone 是从牡丹皮中提取的一种有效成分，具有选择性诱导肿瘤细胞凋亡 (apoptosis) 和抗增殖作用。
Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines.
Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells.
Cell Proliferation Assay
| Cell Line: | TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells |
| Concentration: | 0-30 μM |
| Incubation Time: | 0-72 hours |
| Result: | Significantly decreased the cell proliferation of tumor cell lines and inhibited the proliferation of normal cell lines. |
Apoptosis Analysis
| Cell Line: | TIG-1 and 3T3-L1 (normal cells), HL60, Jurkat, and HeLa cells (tumor cells) |
| Concentration: | 0, 1, 3, 10, 30 μM |
| Incubation Time: | 24 and 72 hours |
| Result: | Induced DNA fragmentation in three tumor cell lines, but not in two normal cell lines. |
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N3119 | 芍药甙元酮 Paeoniflorigenone | 80454-42-8 | 1mg | 8000元 |