纳美芬
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- CAS号:
- 55096-26-9
- 英文名:
- Nalmefene
- 英文别名:
- C08027;NALMEFENE;ORF-11676;nalmetrene;Nalmefene d3;Nalmefene-D7;NalMefene USP;6-Deoxo-6-methylenenaltrexone;6-desoxy-6-methylenenaltrexone;4,5α-Epoxy-6-methylene-17-(cyclopropylmethyl)morphinan-3,14-diol
- 中文名:
- 纳美芬
- 中文别名:
- 纳美芬;(5Α)-17-(环丙基甲基)-4,5-环氧-6-亚甲基吗啡喃-3,14-二醇
- CBNumber:
- CB1747788
- 分子式:
- C21H25NO3
- 分子量:
- 339.44
- MOL File:
- 55096-26-9.mol
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纳美芬化学性质
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熔点:
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182-185?C
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沸点:
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507.9±50.0 °C(Predicted)
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密度:
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1.38±0.1 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
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形态:
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Solid
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酸度系数(pKa):
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pKa 7.63(H2O) (Uncertain)
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颜色:
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White to Off-White
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CAS 数据库:
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55096-26-9
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NIST化学物质信息:
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Nalmefene(55096-26-9)
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纳美芬性质、用途与生产工艺
化学性质
从乙酸乙酯结晶，熔点188～190℃
用途
鸦片受体拮抗剂。
生产方法
纳酮(Naltrexone[16590-41-3])和三苯基甲基溴化镌进行Wittig反应，即得纳美芬。
纳美芬
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纳美芬国内生产厂家
55096-26-9, 纳美芬 相关搜索:
- Pharmaceuticals
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- 药物
- 其它药物
- 解毒药
- C21H22D3NO3
- (5Α)-17-(环丙基甲基)-4,5-环氧-6-亚甲基吗啡喃-3,14-二醇
- 纳美芬
- 55096-26-9
- Nalmefene-D7
- Nalmefene-d3Q: What is
Nalmefene-d3 Q: What is the CAS Number of
Nalmefene-d3
- Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5α)-
- (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
- Morphinan-3,14-diol,17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5a)-
- NalMefene USP
- ORF-11676
- Nalmefene d3
- (5α)-17-(d3-Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
- C08027
- 4,5α-Epoxy-6-methylene-17-(cyclopropylmethyl)morphinan-3,14-diol
- 17-(Cyclopropylmethyl)-4,5α-epoxy-6-methylenemorphinan-3,14-diol
- 9a-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylen-3,14-morphinandiol
- 6-Deoxo-6-methylenenaltrexone
- (5α)-17-(cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
- nalmetrene
- 6-desoxy-6-methylenenaltrexone
- (5alpha)-17-(cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol
- NALMEFENE
- 17-(cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol
- [5ALPHA]-17-[CYCLOPROPYLMETHYL]-4,5-EPOXY-6-METHYLENEMORPHINAN-3,14-DIOL