硫酸类肝素
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- CAS号:
- 9050-30-0
- 英文名:
- Heparitin, sulfate
- 英文别名:
- C00925;Tavidan;Heparitin;Alpha-Idosane;EPARAN SULFATE;Heparan, sulfate;Heparatan sulfate;Heparan N-sulfate;Hepartiin sulfate;Heparitin monosulfate
- 中文名:
- 硫酸类肝素
- 中文别名:
- 硫酸类肝素;硫酸乙酰肝素;硫酸乙酰肝素(98-102%)
- CBNumber:
- CB1931428
- 分子式:
- C14H23NO21S3
- 分子量:
- 0
- MOL File:
- Mol file
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硫酸类肝素化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Aqueous Acid (Slightly), Water (Slightly)
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形态:
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Solid
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颜色:
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White to Off-White
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硫酸类肝素性质、用途与生产工艺
硫酸类肝素是一种复杂的线性多糖。它作为硫酸乙酰肝素蛋白聚糖的一部分出现，在细胞表面和细胞外基质中表达丰富。
Heparan sulfate是一种复杂的线性多糖。它作为硫酸乙酰肝素蛋白聚糖的一部分出现，在细胞表面和细胞外基质中表达丰富。
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Human Endogenous Metabolite
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Heparan sulfate is a linear polysaccharide and belongs to the family of glycosaminoglycans. Heparan sulfate is composed of glucuronic acid (GlcA) and iduronic acid (IdoA) residues as well as N-acetyl glucosamines (GlcNAc) with various sulfation modifications, and is typically 50-200 disaccharides in length. Heparan sulfate interacts with numerous proteins, including growth factors, morphogens, and adhesion molecules, and thereby regulates important developmental processes in invertebrates and vertebrates. Heparan sulfate chains regulate developmental signaling by acting as co-factors through a variety of mechanisms that include but are not limited to maintenance of morphogen gradients and co-receptor functions. Heparan sulfate proteoglycans can act as receptors for proteases and protease inhibitors regulating their spatial distribution and activity. Membrane Heparan sulfate proteoglycans act as coreceptors for various tyrosine kinase-type growth factor receptors, lowering their activation threshold or changing the duration of signaling reactions. Heparan sulfate influences the binding affinity of intestinal epithelium cells to Wnt, thereby promoting activation of canonical Wnt signaling and facilitating regeneration of small intestinal crypts after epithelial injury.
Digestion of heparan sulfate impairs context discrimination in a fear conditioning paradigm and oscillatory network activity in the low theta band after fear conditioning. Thus, heparan sulfate maintains neuronal excitability and, as a consequence, support synaptic plasticity and learning. FGF-2/FGFR system is involved in the regulation of astrocytic reactivity and/or proliferation in the brain and its action is potentiated by heparan sulfate.
硫酸类肝素
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-101916 | Heparan Sulfate | | 1 mg | 500元 |
| 2024/01/25 | HY-101916 | 硫酸类肝素
Heparan Sulfate | 9050-30-0 | 5mg | 1100元 |
9050-30-0, 硫酸类肝素 相关搜索:
- 药靶配体
- 高纯试剂
- 化学试剂
- 化工原料
- C14H23NO21S3
- C12H19NO20S3n
- 硫酸乙酰肝素(98-102%)
- 硫酸乙酰肝素
- 硫酸类肝素
- 9050-30-0
- Hepartiin sulfate
- Fibroblast growth factor receptor,Wnt,Heparan Sulfate,FGFR,Inhibitor,Endogenous Metabolite,Heparan,inhibit
- Heparan Sulfate（98-102%）
- EPARAN SULFATE
- Duodenum Heparinoid USP/EP/BP
- Heparan Sulphate. Parent polymer for HS Fractions above.
- Tavidan
- N-Acetylheparan sulfate
- Heparitin monosulfate
- Heparitin
- Heparatan sulfate
- Heparan N-sulfate
- Alpha-Idosane
- C00925
- Heparan, sulfate