毒胡萝卜素

毒胡萝卜素性质、用途与生产工艺

用途

毒胡萝卜素是广泛使用的肌细胞内质网Ca（2 +）-ATPases抑制剂。 它充当有效的，可渗透细胞的，不依赖IP3的细胞内钙释放剂，可阻止血管生成抑制素和内皮抑素诱导的细胞内Ca2 +的瞬时增加。 它通过破坏细胞内游离Ca2 +水平诱导细胞凋亡。

生物活性

Thapsigargin 是一种有效的、非竞争性的 the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) 的抑制剂，对carbachol诱导的[Ca2+]i瞬变在存不存在KCl预刺激条件下的IC50值分别为0.353 nM和0.448 nM。Thapsigargin 可诱导细胞凋亡。Thapsigargin 提取自植物Thapsia garganica。

靶点

Target	Value
SERCA ()

体外研究

体内研究

毒胡萝卜素 上下游产品信息

上游原料

下游产品

毒胡萝卜素 试剂级价格

更新日期	产品编号	产品名称	CAS编号	包装	价格
2024/04/30	C32857	毒胡萝卜素 5MG Thapsigargin, 97%	67526-95-8	1mg	1634元
2024/04/30	C32857	毒胡萝卜素 5MG Thapsigargin, 97%	67526-95-8	5mg	6212元

毒胡萝卜素 生产厂家

 

67526-95-8, 毒胡萝卜素 相关搜索:

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• (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3...
• THAPSIGARGIN USP/EP/BP
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• Thapsigargin,97%