邻苯二甲酸-1-丁酯-2-异丁酯
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- CAS号:
- 17851-53-5
- 英文名:
- butyl isobutyl phthalate
- 英文别名:
- butyl isobutyl phthalate;n-Butyl iso-butyl phthalate;Butyl-2-methylpropylphthalate;1-Butyl-2-isobutyl Phthalic acid;Phthalic acid 1-butyl 2-isobutyl ester;Phthalic acid 1-(2-methylpropyl)2-butyl ester;n-Butylisobutyl phthalate (n-Butyl-2-methylpropyl phthalate);1,2-Benzenedicarboxylic acid, 1-butyl 2-(2-methylpropyl) ester;hypoglycemic,diabete,α-glucosidase,Inhibitor,Butyl isobutyl phthalate,inhibit,Glucosidase
- 中文名:
- 邻苯二甲酸-1-丁酯-2-异丁酯
- 中文别名:
- 邻苯二甲酸丁基异丁酯;丁基异丁基邻苯二甲酸酯;邻苯二甲酸正丁酯异丁酯;邻苯二甲酸-1-丁酯-2-异丁酯;别名:1-O-丁基2-O-(2-甲基丙基)苯-1,2-二羧酸酯
- CBNumber:
- CB4880190
- 分子式:
- C16H22O4
- 分子量:
- 278.34
- MOL File:
- 17851-53-5.mol
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邻苯二甲酸-1-丁酯-2-异丁酯化学性质
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沸点:
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315.7±10.0 °C(Predicted)
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密度:
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1.051±0.06 g/cm3(Predicted)
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储存条件:
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Sealed in dry,Room Temperature
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溶解度:
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Chloroform (Slightly), Ethyl Acetate (Slightly)
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形态:
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Oil
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颜色:
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Colourless
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邻苯二甲酸-1-丁酯-2-异丁酯性质、用途与生产工艺
Butyl isobutyl phthalate (BIP) 是一种从 Laminaria japonica 的根状茎中分离出来的，α-glucosidase 的非竞争性抑制剂，其IC50值为38 μM。Butyl isobutyl phthalate 具有显著的降血糖作用和治疗糖尿病的潜力。
| Target | Value |
α-glucosidase
(Cell-free assay)
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38 μM
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Butyl isobutyl phthalate exhibits significant, concentration-dependent inhibitory activity against α-glucosidase with an IC
50
value of 38 μM.
Butyl isobutyl phthalate (intragastric administration; 25, 50 or 100 mg/kg; 3 days) results in a more significant reduction in the blood glucose level, with the concentration of blood glucose being 11.50, 8.60 and 6.50 mM, respectively.
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Animal Model:
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Streptozocin induced diabetic mice (Male Kunming mice)
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Dosage:
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25, 50 or 100 mg/kg
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Administration:
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Intragastric administration
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Result:
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Had the observed antidiabetes activity in mice.
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邻苯二甲酸-1-丁酯-2-异丁酯
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-N7377 | 邻苯二甲酸-1-丁酯-2-异丁酯
Butyl isobutyl phthalate | 17851-53-5 | 50mg | 900元 |
| 2024/01/25 | HY-N7377 | 邻苯二甲酸-1-丁酯-2-异丁酯
Butyl isobutyl phthalate | 17851-53-5 | 10mM * 1mLin DMSO | 990元 |
17851-53-5, 邻苯二甲酸-1-丁酯-2-异丁酯 相关搜索:
- 药靶配体
- 合成材料中间体
- 1785-53-5
- 丁基异丁基邻苯二甲酸酯
- 邻苯二甲酸丁基异丁酯
- 别名:1-O-丁基2-O-(2-甲基丙基)苯-1,2-二羧酸酯
- 邻苯二甲酸正丁酯异丁酯
- 邻苯二甲酸-1-丁酯-2-异丁酯
- 17851-53-5
- Butyl-2-methylpropylphthalate
- 1-Butyl-2-isobutyl Phthalic acid
- hypoglycemic,diabete,α-glucosidase,Inhibitor,Butyl isobutyl phthalate,inhibit,Glucosidase
- 1,2-Benzenedicarboxylic acid, 1-butyl 2-(2-methylpropyl) ester
- n-Butylisobutyl phthalate (n-Butyl-2-methylpropyl phthalate)
- n-Butyl iso-butyl phthalate
- Phthalic acid 1-butyl 2-isobutyl ester
- Phthalic acid 1-(2-methylpropyl)2-butyl ester
- butyl isobutyl phthalate