2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸
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- CAS号:
- 64118-84-9
- 英文名:
- 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
- 英文别名:
- 4-HYDROXY DICLOFENAC;4-OHD;4'-OHD;Hydroxydiclofenac;4-HYDROXY DICLOFEC;4'-HYDROXYDICLOFENAC;4'-hydroxydiclofenac;Diclofenac Impurity 15;DICLOFENAC, 4'-HYDROXY-;4'-HYDROXYDICLOFENAC STANDARD
- 中文名:
- 2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸
- 中文别名:
- 羟基双氯芬酸;双氯芬酸杂质7;4-羟基双氯酚酸;4'-羟基双氯芬酸;4'-羟基双氯灭痛;4'-羟基双氯芬酸;4′-羟基双氯芬酸 溶液;4-羟基双氯芬酸(CYP2C9);2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸;2-(2-((2,6-二氯-4-羟基苯基)氨基)苯基)乙酸
- CBNumber:
- CB5672615
- 分子式:
- C14H11Cl2NO3
- 分子量:
- 312.15
- MOL File:
- 64118-84-9.mol
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2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸化学性质
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熔点:
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178-185°C dec.
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沸点:
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432.7±45.0 °C(Predicted)
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密度:
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1.520±0.06 g/cm3(Predicted)
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闪点:
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2℃
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储存条件:
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-20°C
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溶解度:
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Soluble in DMSO, ethanol or methanol
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酸度系数(pKa):
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4.17±0.10(Predicted)
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BRN:
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4198042
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稳定性:
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Light Sensitive
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2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸性质、用途与生产工艺
4'-Hydroxy diclofenac 是具有口服活性的 Diclofenac (HY-15036) 通过细胞色素 P450 2C9 (CYP2C9) 的代谢产物。4'-Hydroxy diclofenac 具有抗炎和镇痛作用。
A single oral administration of Diclofenac to humanized mice, the unchanged drug in plasma peaks at 0.25 hour and then declines with a half-life (t
1/2
) of 2.4 hours. 4'-Hydroxy diclofenac also peaks at 0.25 hour and is undetectable within 24 hours. The plasma concentration of unchanged 4'-Hydroxy diclofenac peaks at 0.25 hour and declines rapidly in Humanized chimeric mice received of 4'-Hydroxy diclofenac (10 mg/kg; a single oral).
2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-15550 | 4'-Hydroxy diclofenac | | 1 mg | 2400元 |
| 2024/01/25 | HY-15550 | 2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸
4'-Hydroxy diclofenac | 64118-84-9 | 5mg | 6000元 |
2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸
生产厂家
64118-84-9, 2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸 相关搜索:
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- Analytical Standards
- HU - HZ
- 4'-羟基双氯芬酸
- 双氯芬酸杂质7
- 4-羟基双氯芬酸(CYP2C9)
- 4-羟基双氯酚酸
- 2-(2-((2,6-二氯-4-羟基苯基)氨基)苯基)乙酸
- 2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸/4'-羟基双氯灭痛
- 4'-羟基双氯芬酸
- 2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸
- 4'-羟基双氯灭痛
- 羟基双氯芬酸
- 4′-羟基双氯芬酸 溶液
- 64118-84-9
- 4'-hydroxydiclofenac
- 4-HYDROXY DICLOFEC
- 4-HYDROXY DICLOFENAC
- 2-(2-((2,6-dichloro-4-hydroxyphenyl)amino)phenyl)acetic acid
- Diclofenac Impurity 15
- 4'-Hydroxydiclofenac VETRANAL(TM), analytical standard
- 4′-Hydroxydiclofenac solution
- Hydroxydiclofenac
- Benzeneacetic acid, 2-[(2,6-dichloro-4-hydroxyphenyl)aMino]-
- 2-(2,6-Dichloro-4-hydroxyanilino)benzeneacetic acid
- [2-(2,6-Dichloro-4-hydroxyanilino)phenyl]acetic acid
- 4'-HYDROXYDICLOFENAC STANDARD
- 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
- 4'-HYDROXYDICLOFENAC
- 4-OHD
- 4'-OHD
- DICLOFENAC, 4'-HYDROXY-
- (o-(2,6-dichloro-4-hydroxyanilino)phenyl)aceticacid
- (o-(2,6-dichloro-4-hydroxyanilino)phenyl)-aceticaci