双醋酚丁
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- CAS号:
- 115-33-3
- 英文名:
- oxyphenisatine di(acetate)
- 英文别名:
- OXYPHENISATIN ACETATE;Isacen;Oxyphenisatin diacetate;(2-oxoindoline-3，3-diyl)bis(4，1-phenylene) dipropionate;sbfd;Levema;Fenisan;Isocrin;Isaphen;Laxocol
- 中文名:
- 双醋酚丁
- 中文别名:
- 双丙酚丁;双醋酚丁;双丙富马酸盐;双醋酚丁衍生物;双醋酚丁 标准品
- CBNumber:
- CB6900715
- 分子式:
- C24H19NO5
- 分子量:
- 401.41
- MOL File:
- 115-33-3.mol
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双醋酚丁化学性质
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熔点:
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244℃
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沸点:
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566.5±50.0 °C(Predicted)
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密度:
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1.282±0.06 g/cm3(Predicted)
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储存条件:
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-20°C Freezer
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溶解度:
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Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
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形态:
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Solid
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酸度系数(pKa):
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13.55±0.40(Predicted)
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颜色:
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White to Off-White
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双醋酚丁性质、用途与生产工艺
双醋酚丁是一种化学物质，临床药品口服后在肠内遇碱性肠液逐渐分解成醋酸和酚丁，酚丁对肠粘膜的刺激作用比酚肽强数十倍，故其导泻作用较强。
Oxyphenisatin acetate是oxyphenisatin的前体药物，过去常用作泻药。
Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468. In the estrogen receptor (ER) positive MCF7 and T47D cells, oxyphenisatin acetate induces TNFα expression and TNFR1 degradation, indicating autocrine receptor-mediated apoptosis in these lines. Ten micromoles per liter Oxyphenisatin acetate treatment results in autophagy and mitochondrial dysfunction.
Oxyphenisatin acetate (300 mg/kg, i.p.) delivers intraperitoneally inhibited tumor growth, accompanied by phosphorylation of eIF2α and degradation of TNFR1 in an MCF7 xenograft model.
双醋酚丁
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-101714 | Oxyphenisatin acetate | | 5 mg | 312元 |
| 2024/01/25 | HY-101714 | 双醋酚丁
Oxyphenisatin acetate | 115-33-3 | 10mg | 500元 |
115-33-3, 双醋酚丁 相关搜索:
- 对照品
- 医药原料
- 通便
- 双丙富马酸盐
- 双丙酚丁
- 双醋酚丁衍生物
- 双醋酚丁 标准品
- 双醋酚丁
- 115-33-3
- Bromhexine Impurity 26
- Autophagy,Oxyphenisatin acetate,inhibit,Inhibitor,Oxyphenisatin
- (2-oxoindoline-3，3-diyl)bis(4，1-phenylene) dipropionate
- Oxyphenisatin diacetate
- Isacen
- OXYPHENISATIN ACETATE
- Dipropumarate
- sbfd
- Oxyphenisatin Diacetate (>90%)
- oxyphenisatine di(acetate) USP/EP/BP
- 2H-Indol-2-one, 3,3-bis[4-(acetyloxy)phenyl]-1,3-dihydro-
- oxyphenisatine di(acetate)
- (2-Oxo-2,3-dihydro-1H-indole-3,3-diyl)di-4,1-phenylene diacetate
- (2-oxoindoline-3,3-diyl)bis(4,1-phenylene) diacetate
- Sanapert
- Purgaceen
- Puragaceen
- Prulet Liquitab
- Promassolax
- Phenlaxine
- NSC 117186
- Lisagal
- Laxo-Isatin
- Laxocol
- Isatin, O,O'-diacetyldiphenol-
- Isaphen
- Fenisan
- Diphesatine
- acetic acid [4-[3-(4-acetoxyphenyl)-2-keto-indolin-3-yl]phenyl] ester
- [4-[3-(4-acetyloxyphenyl)-2-oxo-1H-indol-3-yl]phenyl] ethanoate
- [4-[3-(4-acetyloxyphenyl)-2-oxo-1H-indol-3-yl]phenyl] acetate
- NSC-59687
- Levema
- Isocrin
- 3,3-Bis[4-(acetyloxy)phenyl]-1,3-dihydro-2H-indol-2-one
- Isaphenin
- Isapheninum