579492-81-2
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- CAS号:
- 579492-81-2
- 英文名:
- BAX INHIBITING PEPTIDE V5 (BIP-V5)
- 英文别名:
- Val-Pro-Met-Leu-Lys;VAL-PRO-MET-LEU-LYS;BIP-V5;Bax inhibitor peptide V5 TFA;BAX INHIBITOR PEPTIDE V5, >99%;Bax inhibitor peptide V5 (BIP-V5);BAX INHIBITING PEPTIDE V5 (BIP-V5);L-Lysine, L-valyl-L-prolyl-L-methionyl-L-leucyl-;VAL-PRO-MET-LEU-LYS;BIP-V5;BAX INHIBITING PEPTIDE V5;BAX Inhibiting Peptide V5 >=97% (HPLC), lyophilized powder;Bax inhibitor peptide V5，Val-Pro-Met-Leu-Lys， BIP-V5，BAX Inhibiting Peptide V5
- 中文名:
- 579492-81-2
- 中文别名:
- BAX抑制肽V5;BAX抑制剂肽V5;BAX抑制剂肽V5三氟乙酸盐;H-VAL-PRO-LEU-MET-LYS-OH;BAX INHIBITOR PEPTIDE V5游离态;BIP-V5; BAX INHIBITING PEPTIDE V5;(S)-6-氨基-2-((S)-2-((S)-2-((S)-1-((S)-2-氨基-3-甲基丁酰基)吡咯烷-2-甲酰胺基)-4-(甲硫基)丁酰胺基)-4-甲基戊酰胺)己酸
- CBNumber:
- CB8503178
- 分子式:
- C27H50N6O6S
- 分子量:
- 586.79
- MOL File:
- 579492-81-2.mol
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579492-81-2化学性质
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沸点:
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907.2±65.0 °C(Predicted)
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密度:
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1.185±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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≥29.35 mg/mL in DMSO; insoluble in EtOH; ≥91.4 mg/mL in H2O
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形态:
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lyophilized powder
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酸度系数(pKa):
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3.31±0.10(Predicted)
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579492-81-2性质、用途与生产工艺
Bax inhibitor peptide V5 (BIP-V5) 是一种 Bax 诱导凋亡的抑制剂，主要用于癌症研究。
Bax inhibitor peptide V5 (BIP-V5; 0-50 μM) reduces cell death in STF-cMyc cells but not in SW620 or NCI-H23 cells. BIPV5 does not result in any significant effect on cell cycle arrest at the G2/M phase. V5 treatment upregulates expression of anti-apoptotic proteins Bcl-2 and XIAP by more than 3- and 11-fold and downregulates expression of apoptosis-inducing proteins Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively.
Bax inhibitor peptide V5 (BIP-V5; 100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model.
579492-81-2
上下游产品信息
上游原料
下游产品
579492-81-2, 579492-81-2 相关搜索:
- 药靶配体
- 目录多肽
- 目录肽
- C27H50N6O6S
- BIP-V5; BAX INHIBITING PEPTIDE V5
- BAX抑制剂肽V5三氟乙酸盐
- BAX抑制剂肽V5
- H-VAL-PRO-LEU-MET-LYS-OH
- (S)-6-氨基-2-((S)-2-((S)-2-((S)-1-((S)-2-氨基-3-甲基丁酰基)吡咯烷-2-甲酰胺基)-4-(甲硫基)丁酰胺基)-4-甲基戊酰胺)己酸
- BAX INHIBITOR PEPTIDE V5游离态
- BAX抑制肽V5
- 579492-81-2
- Bax inhibitor peptide V5 TFA
- Bax inhibitor peptide V5，Val-Pro-Met-Leu-Lys， BIP-V5，BAX Inhibiting Peptide V5
- BAX Inhibiting Peptide V5 >=97% (HPLC), lyophilized powder
- L-Lysine, L-valyl-L-prolyl-L-methionyl-L-leucyl-
- VAL-PRO-MET-LEU-LYS;BIP-V5;BAX INHIBITING PEPTIDE V5
- Bax inhibitor peptide V5 (BIP-V5)
- VAL-PRO-MET-LEU-LYS;BIP-V5
- Val-Pro-Met-Leu-Lys
- Bax inhibitor peptide V5,Val-Pro-Met-Leu-Lys, BIP-V5,BAX Inhibiting Peptide V5, >99%
- BAX INHIBITOR PEPTIDE V5, >99%
- BAX INHIBITING PEPTIDE V5 (BIP-V5)