L-高胱氨酸硫内酯盐酸盐
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- CAS号:
- 31828-68-9
- 英文名:
- L-HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE
- 英文别名:
- L-HCT-HCL;H-HOCYS-THIOLACTONE HCL;L-HOMOCYSTEINETHIOLACTONEHCL;-3-Aminodihydrothiophen-2(3H);L-HOMOCYSTEINE THIOLACTONE HCL*CRYST;L-HOMOCYSTEINETHILOACTONEHYDROCHLORIDE;(3S)-3-aminothiolan-2-one hydrochloride;L-HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE;L-HOMOCYSTEINE THIOLACTONE HCL*CRYSTALLI NE;(S)-3-Aminodihydro-2(3H)-thiophenone hydrochloride
- 中文名:
- L-高胱氨酸硫内酯盐酸盐
- 中文别名:
- 高半胱氨酸硫内酯;L-HCT-HCL;化合物 T19393;L-高胱氨酸硫内酯盐酸盐;L-高半胱氨酸硫内酯盐酸盐;L-高半胱氨酸硫代内酯盐酸盐;L-同型半胱氨酸硫内酯 盐酸盐;(S)-3-氨基二氢噻吩-2(3H)-酮盐酸盐
- CBNumber:
- CB9137747
- 分子式:
- C4H8ClNOS
- 分子量:
- 153.63
- MOL File:
- 31828-68-9.mol
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L-高胱氨酸硫内酯盐酸盐化学性质
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熔点:
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185-191 °C
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储存条件:
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Keep in dark place,Inert atmosphere,Room temperature
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溶解度:
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Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
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形态:
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Solid
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颜色:
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Pale Beige
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BRN:
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3911455
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稳定性:
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Hygroscopic
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L-高胱氨酸硫内酯盐酸盐性质、用途与生产工艺
L-Homocysteine thiolactone hydrochloride是同型半胱氨酸的分子内硫酯; 防止同型半胱氨酸转化成蛋白质。
In all cell types, from bacterial to human, homocysteine is metabolized to homocysteine thiolactone by methionyl-tRNA synthetase. Elevated levels of homocysteine are an independent risk factor for cardiovascular disease in humans. Homocysteine can be harmful to human cells because of its metabolic conversion to homocysteine thiolactone, a reactive thioester. This conversion occurs in all human cell types, including endothelial cells. Homocysteine thiolactone induces cell death and features of apoptosis including increased phosphotidylserine exposure on the membrane surface, increased apoptotic cells with hypoploid DNA contents, and internucleosomal DNA fragmentation in HL-60 cells. Homocysteine thiolactone is cytotoxic and capable of promoting cell death, as measured by caspase-3 activation and DNA fragmentation. HcyT strongly activates IL-8 release.
Homocysteine thiolactone is toxic, induces epileptic seizures in rodents, and has been implicated in Alzheimer’s disease. Homocysteine thiolactone induces two types of seizures, the coexistence of convulsive and nonconvulsive epilepsy. The grade of seizures is dose dependent.
L-高胱氨酸硫内酯盐酸盐
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上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-101404A | L-高胱氨酸硫内酯盐酸盐
L-Homocysteine thiolactone hydrochloride | 31828-68-9 | 5mg | 325元 |
| 2024/01/25 | HY-101404A | L-高胱氨酸硫内酯盐酸盐
L-Homocysteine thiolactone hydrochloride | 31828-68-9 | 10mg | 520元 |
31828-68-9, L-高胱氨酸硫内酯盐酸盐 相关搜索:
- 生化试剂
- Unnatural Amino Acid Derivatives
- Specialty Synthesis
- Peptide Synthesis
- Homo-Amino Acids
- C4H8ClNOS
- 31828-69-9
- L-HCT-HCL
- (S)-3-氨基二氢噻吩-2(3H)-酮盐酸盐
- 化合物 T19393
- L-同型半胱氨酸硫内酯 盐酸盐
- L-高半胱氨酸硫代内酯盐酸盐
- 高半胱氨酸硫内酯
- L-高半胱氨酸硫内酯盐酸盐
- L-高胱氨酸硫内酯盐酸盐
- 31828-68-9
- L-HCT-HCL
- LHomocysteine thiolactone hydrochloride,L Homocysteine thiolactone hydrochloride
- (3S)-3-aminothiolan-2-one hydrochloride
- L-2-AMINO-4-MERCAPTOBUTYRIC ACID 1,4-THIOLACTONE HYDROCHLORIDE
- L-HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE
- L-HOMOCYSTEINETHIOLACTONEHCL
- L-HOMOCYSTEINETHILOACTONEHYDROCHLORIDE
- L-HOMOCYSTEINE THIOLACTONE HCL*CRYSTALLI NE
- L-HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE ULTRA-PURE
- (S)-3-aminodihydrothiophen-2(3H)-one hydrochloride
- 2(3H)-THIOPHENONE, 3-AMINODIHYDRO-, HYDROCHLORIDE, (S)-
- 2(3H)-THIOPHENONE, 3-AMINODIHYDRO-, HYDROCHLORIDE, L-
- 2(3H)-THIOPHENONE, 3-AMINODIHYDRO-, HYDROCHLORIDE, (3S)-
- H-HOCYS-THIOLACTONE HCL
- -3-Aminodihydrothiophen-2(3H)
- L-HOMOCYSTEINE THIOLACTONE HCL*CRYST
- (S)-3-Aminodihydro-2(3H)-thiophenone hydrochloride
- CAindexname:2(3H)-Thiophenone,3-aminodihydro-,hydr
- L-Homocysteine thiolactone hydrochloride,L-2-Amino-4-mercaptobutyric acid 1,4-thiolactone hydrochloride