串珠镰刀菌素
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- CAS号:
- 71376-34-6
- 英文名:
- 1-HYDROXYCLOBUT-1-ENE-3,4-DIONE SODIUM SALT
- 英文别名:
- Ccris 7906;Moniliformin Sodium;MONILIFORMIN SODIUM SALT;sodiumsaltofmoniliformin;MONILIFOMIN POTASSIUM SALT;Moniliformin (Natrium salt);Moniliformin sodium salt solution;1-hydroxycyclobut-1-ene-3,4-dione;Moniliformin in acetonitrile/water;Sodium 3,4-dioxocyclobut-1-en-1-olate
- 中文名:
- 串珠镰刀菌素
- 中文别名:
- 串珠镰刀菌素;串珠镰刀菌素钠盐;串珠镰刀菌素钾盐;化合物 T13777;串珠镰刀菌素钠盐标准溶液;3-羟基-3-环丁烯二酮钠盐;串珠镰刀菌素钾盐, 来源于镰刀菌;MONILIFORMIN (NATRIUM SALT);MONILIFORMIN SODIUM SALT BIOCHEMICA
- CBNumber:
- CB9200829
- 分子式:
- C4H3NaO3
- 分子量:
- 122.05
- MOL File:
- 71376-34-6.mol
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串珠镰刀菌素化学性质
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闪点:
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2℃
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储存条件:
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2-8°C
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溶解度:
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≤10mg/ml in H2O
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形态:
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Light yellow powder.
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串珠镰刀菌素性质、用途与生产工艺
串珠镰刀菌素对动物有较强的毒性作用，主要作用于增殖活跃的细胞，例如心肌、肝、脾、骨骼肌以及软骨细胞和骨细胞等。
Moniliformin sodium salt是提取自镰孢镰刀菌中的有效，水溶性的霉菌毒素。
Fusarium moniliforme
NRRL 6322 produces about 600 mg of recoverable moniliformin, a mycotoxic metabolite, per kg of corn grit medium. Several strains of
Fusarium moniliforme
produce in laboratory culture more than 800 mg of moniliformin per kg of growth substrate. Monocytes-derived macrophages exposed to moniliformin during the differentiation process present a decrease of endocytosis ability, and a decrease of CD71 and HLA-DR expression.
Moniliformin is less toxic to mice, with an LD
50
of 20.9 mg per kg for the females and 29.1 mg per kg of body weight for the males. As in the case of the chicks, mice surviving the toxin demonstrated no ill effects; the mice or chicks that died became recumbent in 4 to 6 h after treatment and died within 24 h. In 4-day-old chicken embryos, a sharp LD
50
of 2.8 μg per embryo is obtained with no overt gross teratogenic effects in the survivors. Rats treated with the highest dose of moniliformin show decreased activity followed by acute heart failure and death. The rats of the lower doses (<9mg/kg b.w.) show no signs of toxicity. The daily intake of moniliformin strongly reduces the phagocytic activity of neutrophils in all dose groups. The decrease continued in the satellite group during the follow-up period, indicating a severe impact on the immune system and a LOAEL value of 3mg/kg b.w. for moniliformin. Moniliformin is rapidly excreted into urine, ranging between 20.2 and 31.5% daily and shows no signs of accumulation. The concentration of moniliformin in faeces is less than 2%, which suggests efficient absorption from the gastrointestinal tract.
串珠镰刀菌素
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-101905 | 串珠镰刀菌素
Moniliformin sodium salt | 71376-34-6 | 1mg | 2100元 |
| 2024/01/25 | HY-101905 | 串珠镰刀菌素
Moniliformin sodium salt | 71376-34-6 | 10mM * 1mLin DMSO | 2773元 |
71376-34-6, 串珠镰刀菌素 相关搜索:
- antibiotic
- 医药原料
- 抗生素
- 微生物代谢物
- C4H1O3Na
- C4HO3K
- C4HNaO3
- C4HO3Na
- 串珠镰刀菌素钠盐标准溶液
- MONILIFORMIN (NATRIUM SALT)
- 串珠镰刀菌素钠盐
- 串珠镰刀菌素钾盐, 来源于镰刀菌
- MONILIFORMIN SODIUM SALT BIOCHEMICA
- 化合物 T13777
- 串珠镰刀菌素钾盐
- 串珠镰刀菌素
- 3-羟基-3-环丁烯二酮钠盐
- 71376-34-6
- Moniliformin in acetonitrile/water
- Moniliformin (Natrium salt)
- Moniliformin Sodium
- Monilifomin potassium salt, 98%, from Fusarium proliferatum
- 1-hydroxycyclobut-1-ene-3,4-dione
- moniliformin sodium from fusarium*proliferatum
- sodiumsaltofmoniliformin
- 2-dione,3-hydroxy-3-cyclobutene-sodiumsalt
- 1-HYDROXYCLOBUT-1-ENE-3,4-DIONE SODIUM SALT
- Moniliformin sodium salt solution
- Moniliformin 3-Hydroxy-3-cyclobutenedione sodium salt
- 1-hydroxycyclobut-1-ene-3,4-dionesodiumsalt
- MONILIFORMIN SODIUM SALT
- MONILIFOMIN POTASSIUM SALT
- Sodium 3,4-dioxocyclobut-1-en-1-olate
- Moniliformin sodium salt from Fusarium proliferatum,1-Hydroxycyclobut-1-ene-3,4-dione
- Ccris 7906
- 3-Hydroxy-3-cyclobutenedione sodium salt
- 3-Cyclobutene-1,2-dione, 3-hydroxy-, sodium salt
- monobutyryl cyclic 3',5'-adenosine monophosphate, sodium
- Moniliformin sodium salt from Fusarium moniliforme
- moniliformin sodium salt from fusarium proliferatum