CYCLO(-PRO-VAL)

CYCLO(-PRO-VAL) Struktur
2854-40-2
CAS-Nr.
2854-40-2
Englisch Name:
CYCLO(-PRO-VAL)
Synonyma:
Cyclo(Val-Pro);CYCLO(-PRO-VAL);Cyclo(L-Val-L-Pro-);Cyclo(L-Pro-L-Val-);2854-40-2/5654-87-5;Cyclo(L-prolyl-L-valyl);CYCLO(L-PROLYL-L-VALINE);Cyclo(L-Pro-L-Val),CYCLO(-PRO-VAL);(3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione;(3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
CBNumber:
CB0132749
Summenformel:
C10H16N2O2
Molgewicht:
196.25
MOL-Datei:
2854-40-2.mol

CYCLO(-PRO-VAL) Eigenschaften

Schmelzpunkt:
190-192 °C
Siedepunkt:
420.7±34.0 °C(Predicted)
Dichte
1.17±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Löslichkeit
Chloroform (Slightly, Sonicated), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.15±0.40(Predicted)
Farbe
White to Off-White
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

CYCLO(-PRO-VAL) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Cyclo(L-Pro-L-Val) is a diketopiperazine that has been found in the marine sponge T. ignis, the bacterium B. pumilus, and the fungus A. fumigatus, among others. It is active against the bacteria S. aureus and B. subtilis (MICs = 16.3 and 18.2 μg/ml, respectively) but not E. coli (MIC = >20 μg/ml). Cyclo(L-Pro-L-Val) inhibits activation of a LuxR-dependent E. coli biosensor by the quorum-sensing molecule 3-oxo-hexanoyl-homoserine lactone (IC50 = 0.4 mM) and activates violacein pigment production in the LuxR-dependent C. violaceum acyl homoserine lactone reporter strain CV026. However, it does not activate or inhibit lacZ-based reporter fusions in S. liquefaciens or A. tumefaciens.

Verwenden

Cyclo(L-Pro-L-Val) is a diketopiperazine formed by the fusion of valine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Pro-L-Val) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Pro-L-Val) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of the cyclo(L-Pro-L-Val) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.

CYCLO(-PRO-VAL) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CYCLO(-PRO-VAL) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 65)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
+16314854226
inquiry@bocsci.com United States 19743 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10523 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634
Cecilia@youngshechem.com China 2345 58
LEAP CHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 24738 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49739 58
Zhejiang Hangyu API Co., Ltd
+8617531972939
anna@api-made.com China 2944 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416
ymbetter@glbiochem.com China 9981 64
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15421 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66099280 17798518460
cfzhang@aikonchem.com China 19918 55

2854-40-2()Verwandte Suche:


  • CYCLO(-PRO-VAL)
  • (3S,8aS)-3-Isopropyl-6,7,8,8aα-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
  • (3S,8aS)-3β-Isopropyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
  • (3S,8aS)-Octahydro-3-(1-methylethyl)pyrrolo[1,2-a]pyrazine-1,4-dione
  • (3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-Pro-L-Val-)
  • Cyclo(L-Val-L-Pro-)
  • Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aS)-
  • (3S,8aS)-3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-prolyl-L-valyl)
  • CYCLO(L-PROLYL-L-VALINE)
  • (3S,8aS)-3-(propan-2-yl)-octahydropyrrolo[1,2-a]p yrazine-1,4-dione
  • (3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-Pro-L-Val),CYCLO(-PRO-VAL)
  • 2854-40-2/5654-87-5
  • Cyclo(Val-Pro)
  • 2854-40-2
Copyright 2019 © ChemicalBook. All rights reserved