BORRELIDIN
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- CAS-Nr.
- 7184-60-3
- Englisch Name:
- BORRELIDIN
- Synonyma:
- Aids128115;BORRELIDIN;NSC 216128;Aids-128115;BORRELIDINE;TREPONEMYCIN;Antispirochetin;Quinquangulin K 182;Quinquangulin K 031;BORRELIDIN USP/EP/BP
- CBNumber:
- CB1134351
- Summenformel:
- C28H43NO6
- Molgewicht:
- 489.64
- MOL-Datei:
- 7184-60-3.mol
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BORRELIDIN Eigenschaften
- Schmelzpunkt:
- 143-145℃
- Siedepunkt:
- 584.45°C (rough estimate)
- Dichte
- 1.1362 (rough estimate)
- Brechungsindex
- 1.6290 (estimate)
- storage temp.
- −20°C
- Löslichkeit
- DMSO: 1 mg/mL
- Aggregatzustand
- White to off-white powder.
- pka
- 4.56±0.40(Predicted)
- Farbe
- Off-white
- Stabilität:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
BORRELIDIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Borrelidin is an unusual nitrile-containing metabolite isolated from Streptomyces. Originally discovered as active against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery, displaying activity against drug-resistant Plasmodia.
Definition
ChEBI: A macrolide that is isolated from several Streptomyces species and displays antibiotic, antineoplastic and antimalarial properties.
Allgemeine Beschreibung
Chemical structure: macrolide
BORRELIDIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Cyclopentanecarboxylic acid, 2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11, 13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-, 2-(trimethylsilyl)ethyl ester, (1R,2R)-
1,2-Cyclopentanedicarboxylic acid, 1,2-dimethyl ester, (1R,2R)-
1-Pentanol, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,4-dimethyl-, (2S,4R)-
(1R,2R)-1,2-Cyclopentanedimethanol
1,2-Cyclopentanedicarboxylic acid, 4-oxo-, 1,2-diMethyl ester, (1R,2R)-
Downstream Produkte
BORRELIDIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 73)Lieferanten
7184-60-3()Verwandte Suche:
- 2-(7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADECA-4,6-DIEN-2-YL)-CYCLOPENTANECARBOXYLIC ACID
- BORRELIDIN
- BORRELIDINE
- 2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid
- Aids128115
- Aids-128115
- Cyclopentanecarboxylic acid, 2-(7-cyano-8, 16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4, 6-dien-2-yl)-
- Quinquangulin K 031
- Quinquangulin K 182
- NSC 216128
- TREPONEMYCIN
- TreponeMycin, U 78548, C2989
- Borrelidin, froM StreptoMyces sp.
- NSC 216128 Borrelidin Treponemycin
- (1R,2R)-2-((2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)cyclopentanecarboxylic acid
- Borrelidin, 99%, from Streptomyces sp.
- Cyclopentanecarboxylic acid, 2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-, (1R,2R)-
- BORRELIDIN USP/EP/BP
- Antispirochetin
- 7184-60-3
- C28H43NO6
- Antibiotics
- Antibiotics A to Z
- Antibiotics A-F
- BioChemical
