3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone

170713-71-0

CAS-Nr.: 170713-71-0

Englisch Name:: 3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone

Synonyma:: Aureusimine B;6-BENZYL-3-ISOPROPYLPYRAZIN-2-ONE;6-benzyl-3-isopropylpyrazin-2(1H)-one;3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone;2(1H)-Pyrazinone, 3-(1-methylethyl)-6-(phenylmethyl)-

CBNumber:: CB12682115

Summenformel:: C14H16N2O

Molgewicht:: 228.28964

MOL-Datei:: 170713-71-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 41

3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone Eigenschaften

Schmelzpunkt:: 117-118 °C

Dichte: 1.10±0.1 g/cm3(Predicted)

storage temp.: Refrigerator

Löslichkeit: Chloroform (Slightly), Methanol (Slightly)

Aggregatzustand: Solid

pka: 11.65±0.60(Predicted)

Farbe: Off-White to Light Grey

Sicherheit

3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide synthetase that creates a dipeptide (phenylalanine-valine) aldehyde, which then undergoes cyclization and oxidation. Aureusimine B inhibits calpain in a casein hydrolysis assay (IC₅₀ = 1.3 μM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression.

Verwenden

Aureusimine B is a novel small molecule isolated from S. aureus as one of a pair of related metabolites controversially identified as virulence factors in the pathology of Golden Staph. Aureusimine B has also been reported as an inhibitor of the protease, calpain.

3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 41)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
AstaTech (Chengdu) Pharma. Co., Ltd.	028-85122536 15928766785	wupengcheng@astatech.cn	China	2002	55
SanoChem (Chengdu) Tech. Co., Ltd.	28-87999436 02887999436	sales@sano-chem.com	China	3929	55
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Nanjing KaiMubo Pharmaceutical Co., Ltd.	025-66162170		China	7183	55
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shanghai He Huan Chemical Co., Ltd.	021-60345187 13917602471	lzz841106@aliyun.com	China	9907	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58

3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone
Aureusimine B
6-BENZYL-3-ISOPROPYLPYRAZIN-2-ONE
6-benzyl-3-isopropylpyrazin-2(1H)-one
2(1H)-Pyrazinone, 3-(1-methylethyl)-6-(phenylmethyl)-
170713-71-0