SCHIZOZYGINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
The major alkaloid obtained from the bark and roots of Schizozygia caffaeoides (Boj.) Baill. The base has [α]
23D + 15.5° (c 1.0, CHC1
3) and gives an ultraviolet spectrum having absorption maxima at 269 and 313 mil. The alkaloid possesses both antipyretic and broncholytic properties. When hydrogenated in AcOH in the presence of Pt0
2 it yields the dihydro derivative, m.p. 190-1°C;[α]
24D + 29.4° (c 1.0, CHCI
3). Hydrogenation with LiAIH
4, however, gives deoxoschizozygine, m.p. 213-233°C (dec.); [α]
26D + 82.9° (c 1.0, CHCI
3). The two reduction processes are protected by patents.
Einzelnachweise
Renner, Kernweisz., Experientia, 19,244 (1963)
Structure:
Renner., Lloydia, 27,406 (1964)
Renner., Swiss Patent 451,182,15 May 1968
Renner., Swiss Patent 451,183,15 May 1968
SCHIZOZYGINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
