Trioxysalen

Trioxysalen Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R34:Verursacht Verätzungen.
R40:Verdacht auf krebserzeugende Wirkung.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).

Chemische Eigenschaften

White to slightly beige crystalline powder

Verwenden

Trioxsalen has been used:

• to induce small deletion mutations in worms
• in combination with ultraviolet A (UVA)
• to induce interstrand crosslinks (ICLs) in DNA
• for the preparation and photoactivation of trimethyl psoralen

Definition

ChEBI: 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phot therapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermi .

Indications

Trioxsalen (Trisoralen) followed by UVA exposure is used to repigment vitiliginous areas and in photochemotherapy.

läuterung methode

Purify trioxsalen by recrystallisation from CHCl3. If too impure, it is fractionally crystallised from CHCl3/pet ether (b 30-60o) using Norit and finally crystallised from CHCl3 alone to give colourless prisms, m 234.5-235o. It is a photosensitiser so it should be stored in the dark. [UV: Kaufmann J Org Chem 26 117 1961, Baeme et al. J Chem Soc 2976 1949, Beilstein 19/4 V 472.]

Trioxysalen Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Trioxysalen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shaanxi Dideu Medichem Co. Ltd	18192627656	1012@dideu.com	China	3320	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29067	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9116	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58

3902-71-4(Trioxysalen)Verwandte Suche:

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• TRISORALEN
• TRIOXSALEN
• TRIOXYSALEN
• 2',4,8-Trimethylpsoralen
• 2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one
• 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one
• 2,5,9-TRIMETHYL-FURO[3,2-G]BENZOPYRAN-7-ONE
• 2,5,9-TRIMETHYL-FUROL[3,2-G]BENZOPYRAN-7-ONE
• 2,5,9-TRIMETHYLPSORALEN
• TRIOXSALEN, FOR FLUORESCENCE
• 4,5',8-Trimethylpsoralen, 97.50%
• TRIOXSALEN,USP
• TRIOXSALEN (4,5,8-TRIMETHYLPSORALEN)
• 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one, 4,5μ,8-Trimethylpsoralen, TMP, Trisoralen
• 4,2',8-Trimethylpsoralen
• 4,5',8-Trimethylpsoralen,97.5%
• 4,5,8-Trimethylpsoralen ,99%
• Trioxsalen (200 mg)
• TMP 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one 4,5',8-Trimethylpsoralen Trisoralen
• 2’,4,8-trimethylpsoralen
• 2-g)(1)benzopyran-7-one,2,5,9-trimethyl-7h-furo(
• 2-g][1]benzopyran-7-one,2,5,9-trimethyl-7h-furo[
• 4,5',8-Trimethylpsoralene
• 5-Benzofuranacrylic acid, 6-hydroxy-beta,2,7-trimethyl-, delta-lactone
• 6-hydroxy-beta,2,7-trimethyl-5-benzofuranacrylicacidgamma-lactone
• 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-
• Benzofuranacrylic acid,6-hydroxy-b,2,7-trimethyl-,
• Elder 8011
• LACTONE
• NSC-71047
• psoralen,4,5’,8-trimethyl-
• Trimethylpsoralen
• Trioxalen
• Trioxsale
• TRIOXSALIN
• Trixsalen
• 4,5',8-TRIMETHYLPSORALEN
• 4,5,8-TRIMETHYLPSORALEN
• )-7-Cyano-17-hydroxy-3-oxo-pregna-4,9(11)-diene-21-carboxylic acid &gamma
• 3,13-Dihydroxy-13,17-secoandrost-5-en-17-oic Acid &delta
• 2,3-Dideoxy-2-methylene-D-glycero-D-galacto-nononic acid &gamma
• 5-O-(1-Methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-D-ribonic Acid &gamma
• 11,12-Dihydro-11-hydroxyretinoic Acid &delta
• 17-Hydroxy-3-oxo-17&alpha
• -pregna-4,20-diene-21-carboxylic Acid &gamma
• Homogentisic Acid &gamma
• N-Boc L-Serine b-Lactone ([(3S)-2-oxo-3-oxetanyl]-1,1-dimethylethyl Ester Carbamic Acid, |N-(tert-Butoxycarbonyl)-L-serine ß
• 4-tert-Butyldimethylsilyl-6&rsquo
• -carboxy-5&rsquo
• -hydroxy Simvastatin &gamma
• rioxsalen
• TRIOXSALEN ISO 9001：2015 REACH
• TrioxsalenQ: What is Trioxsalen Q: What is the CAS Number of Trioxsalen Q: What is the storage condition of Trioxsalen Q: What are the applications of Trioxsalen
• 2,5,9-trimethylfuro[3,2-g]chromen-7-one
• Trioxsalen (1693009)
• 16-Deacetylfusidic Acid &gamma
• 2,5,9-trimethyl-7-furo[3,2-g][1]benzopyranone
• 6-Hydroxy-5-iodo-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid &gamma