Enoxaparin sodium
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- CAS-Nr.
- 679809-58-6
- Englisch Name:
- Enoxaparin sodium
- Synonyma:
- Clexane;ENOXAPARIN SODIUM, EP STANDARD;Enoxil;Klexane;Lovenox;Unii-8nz41mik1o;ENOXAPARIN SODIUM;Enoxaparin SodiuM EP;Lovenox (preservative free);Enoxaparin Sodium (1235820)
- CBNumber:
- CB1994513
- Summenformel:
- C57H82N4Na4O53S3
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Enoxaparin sodium Eigenschaften
- Schmelzpunkt:
- >191°C (dec.)
- storage temp.
- Room Temperature, Under inert atmosphere
- Löslichkeit
- Water (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht außerhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P321 |
Besondere Behandlung |
| P333+P313 |
Bei Hautreizung oder -ausschlag: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
| P363 |
Kontaminierte Kleidung vor erneutem Tragen waschen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Enoxaparin sodium Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Enoxaparin sodium is the sodium salt of a low-molecular-mass heparin that is obtained by alkaline depolymerisation of the benzyl ester derivative of heparin from porcine intestinal mucosa. Enoxaparin sodium is an antithrombotic agent (ATC code B01AB05) characterized by a higher ratio of antithrombotic activity to anticoagulant activity compared to unfractionated heparin.
Specifically, Enoxaparin sodium as the sodium salt of depolymerized Heparin is subject to characteristic structural modifications from the effects of the depolymerization reaction. Characteristic structures such as partial transformation of glucosamines into mannosamines, formation of 1,6-anydro derivatives and 2,3 epoxide residues with subsequent conversion to galacturonic acid and the change in the proportion of the sulfated and non-sulfated residues are some of the changes that constitute Enoxaparin a structurally difficult to characterize molecule. As such no single technique or parameter is adequate to fully characterize the Enoxaparin molecule as part of a biosimilarity exercise against the reference.
Chemische Eigenschaften
degree of sulphatation is ~ 2 per disaccharide
Verwenden
Enoxaparin is marketed under the brand name Lovenox and as a generic drug under the name enoxaparin sodium for injection.
Enoxaparin sodium is intended for use in the treatment of deep vein thrombosis; prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, and treatment of acute deep vein thrombosis.
Indications
Enoxaparin sodium is a gold standard for antithrombosis which has the largest number of indications among all LMWHs. Prophylaxis of vein thrombosis diseases (prevent intra-vein thrombosis), treatment of deep venous thrombosis, Prevention of thrombus formation in the in vitro circulation during hemodialysis, treatment of acute unstable angina and non-Q-wave myocardial infarction, administered with Aspirin.
Enoxaparin sodium Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Enoxaparin sodium Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 109)Lieferanten
679809-58-6()Verwandte Suche:
Ethylisocyanacetat
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium
Tris(pentan-2,4-dionato)eisen(II)
Benzylisocyanid
Methylisocyanacetat
2-Methylpropylisocyanid
Phenylselenol
N-Butylisocyanid
Kupfer(II)-4-oxopent-2-en-2-olat
Dichloro(ethylendiamin)platin
(Pentan-2,4-dionato-O,O')silber
(Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II)
1,1,3,3-Tetramethylbutylisocyanat
(p-Toluolsulfonyl)methylisocyanid
Aluminiumtris(2,4-pentandionato-O,O')
- Lovenox
- Lovenox (preservative free)
- Unii-8nz41mik1o
- Enoxil
- Klexane
- Enoxaparin SodiuM EP
- ENOXAPARIN SODIUM
- Enoxaparin sodiumQ: What is
Enoxaparin sodium Q: What is the CAS Number of
Enoxaparin sodium Q: What is the storage condition of
Enoxaparin sodium
- Enoxaparin Sodium (1235820)
- ENOXAPARIN SODIUM, EP STANDARD
- Clexane
- Enoxaparin sodium (9CI, ACI)
- traumatic brain injury,infection,coronavirus,Inhibitor,PK-10169,Thrombin,inhibit,SARS-CoV,Enoxaparin sodium,Enoxaparin,neuroprotective,Liver fibrosis,Fxa,PK 10169,Inflammation,PK10169,SARS coronavirus,acute coronary syndromes,Factor Xa,Lovenox,blood clots,COVID-19,Thioacetamide
- 679809-58-6
- C57H82N4Na4O53S3
- Other APIs
