5-Aziridino-2,4-dinitrobenzamide

21919-05-1

CAS-Nr.: 21919-05-1

Englisch Name:: 5-Aziridino-2,4-dinitrobenzamide

Synonyma:: CB-954;CB-1954;tretazicar;NSC 115829;CB 1954;CB-1954;Tretazicar (>Tretazicar (>94%);CB1954(TRETAZICAR);Tretazicar (CB 1954);5-Aziridino-2,4-dinitrobenzamide

CBNumber:: CB31216241

Summenformel:: C9H8N4O5

Molgewicht:: 252.18

MOL-Datei:: 21919-05-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 88

5-Aziridino-2,4-dinitrobenzamide Eigenschaften

Schmelzpunkt:: 173 °C

Siedepunkt:: 427.2±45.0 °C(Predicted)

Dichte: 1.671±0.06 g/cm3(Predicted)

storage temp.: -20°C

Löslichkeit: Acetonitrile (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

pka: 14.23±0.50(Predicted)

Aggregatzustand: solid

Farbe: Yellow to Dark Yellow

InChIKey: WOCXQMCIOTUMJV-UHFFFAOYSA-N

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

WGK Germany	3
HS Code	2933.99.7500

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H302	Gesundheitsschädlich bei Verschlucken.	Akute Toxizität oral	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P270, P301+P312, P330, P501

Sicherheit

P280	Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338	BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

5-Aziridino-2,4-dinitrobenzamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

CB-1954 is a prodrug that is enzymatically activated to generate an antitumor agent that forms DNA-DNA interstrand crosslinks. In rat Walker 256 carcinoma cells, CB-1954 is reduced by NAD(P)H:quinone oxidoreductase (NQO1) to the cytotoxic derivative 5-(aziridin-1-yl)-4-hydroxylamineo 2 nitrobenzamide, a bifunctional alkylating agent.

Verwenden

5-Aziridino-2,4-dinitrobenzamide is an anticancer prodrug used in gene therapy research and is known to be activated by NAD(P)H Quinone Oxidoreductase 2.

Biochem/physiol Actions

CB 1954 is an anticancer prodrug used in gene therapy research; activated by NAD(P)H quinone oxidoreductase?2.

5-Aziridino-2,4-dinitrobenzamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5-Aziridino-2,4-dinitrobenzamide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 88)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Changzhou PBpharmaceutical R&D Co.,Ltd	0519-83990708	info@pbpharm.com	CHINA	498	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58

21919-05-1()Verwandte Suche:

CHLOANTRANILIPROLE Benzamid Silan Azetidin Propylbenzol 2,4-Dinitrobenzaldehyd 1-Phenylaziridin

5-(1-aziridinyl)-2,4-dinitrobenzamide
NSC 115829
tretazicar
5-(1-Aziridinyl)-2,4-dinitrobenzamide, 5-(Aziridin-1-yl)-2,4-dinitrobenzamide
5-Aziridino-2,4-dinitrobenzamide
2,4-Dinitro-5-(aziridine-1-yl)benzamide
CB-954
CB-1954
5-(Aziridin-1-yl)-2,4-dinitrobenzamide
Benzamide, 5-(1-aziridinyl)-2,4-dinitro-
2,4-Dinitro-5-ethyleneiminobenzamide
Tretazicar (>94%)
Tretazicar (CB 1954)
CB 1954;CB-1954
CB1954(TRETAZICAR)
Tretazicar (>
Tretazicar,NQO1,DNA Alkylator/Crosslinker,rat,bifunctional,Inhibitor,inhibit,agent,cross-link,256,line,4-hydroxylamine,Walker,CB 1954,DNA,CB-1954,tumour
21919-05-1