3-β,17-α-Dihydroxypregn-5-en-20-on

387-79-1

CAS-Nr.: 387-79-1

Bezeichnung:: 3-β,17-α-Dihydroxypregn-5-en-20-on

Englisch Name:: 17ALPHA-HYDROXYPREGNENOLONE

Synonyma:: NSC 63853;17-OH PREG;17alpha-Hydroxy;17-OH Pregnenolone;Dronedarone HCl-d6;Hydroxypregnenolone;17a-Hydroxypregnolone;17A-HYDROXYPREGENOLONE;17-HYDROXYPREGNENOLONE;17α-Hydroxypregnenolone

CBNumber:: CB3175435

Summenformel:: C21H32O3

Molgewicht:: 332.48

MOL-Datei:: 387-79-1.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 91

3-β,17-α-Dihydroxypregn-5-en-20-on Eigenschaften

Schmelzpunkt:: 273℃

Flammpunkt:: 9℃

storage temp.: -20°C

Löslichkeit: Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated)

Aggregatzustand: Solid

Siedepunkt:: 478.4±45.0 °C(Predicted)

Dichte: 1.15±0.1 g/cm3(Predicted)

pka: 13.02±0.70(Predicted)

Farbe: White to Off-White

CAS Datenbank: 387-79-1(CAS DataBase Reference)

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Kennzeichnung gefährlicher	F,T
R-Sätze:	11-23/24/25-39/23/24/25
S-Sätze:	7-16-36/37-45
RIDADR	UN1230 - class 3 - PG 2 - Methanol
WGK Germany	3
RTECS-Nr.	TU5548000

Bildanzeige (GHS)

Alarmwort

Achtung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H225	Flüssigkeit und Dampf leicht entzündbar.	Entzündbare Flüssigkeiten	Kategorie 2	Achtung	src="/GHS02.jpg" width="20" height="20" />	P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370	Schädigt die Organe.	Spezifische Zielorgan-Toxizität (einmalige Exposition)	Kategorie 1	Achtung	src="/GHS08.jpg" width="20" height="20" />	P260, P264, P270, P307+P311, P321,P405, P501

Sicherheit

P210	Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P260	Dampf/Aerosol/Nebel nicht einatmen.
P280	Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P310	BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P311	GIFTINFORMATIONSZENTRUM/Arzt anrufen.

3-β,17-α-Dihydroxypregn-5-en-20-on Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; ). It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.

Verwenden

17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.

Allgemeine Beschreibung

17α-hydroxypregnenolone is a derived from pregnenolone.

3-β,17-α-Dihydroxypregn-5-en-20-on Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Androst-5-ene-17-carbonitrile, 3-(acetyloxy)-17-hydroxy-, (3β,17α)- (9CI) Pregn-5-en-20-one, 3-(acetyloxy)-16-bromo-17-hydroxy-, (3β)- (9CI) Pregn-5-en-20-one, 17-hydroperoxy-3-hydroxy-, (3β)- (9CI) Pregn-5-en-20-one,16-bromo-3,17-dihydroxy-, (3b,16b)- (9CI) 3-β,17-α-Dihydroxypregn-5-en-20-on-3-acetat 16-α,17-α-Epoxy-3-β-hydroxypregn-5-en-20-on 3,17-DIHYDROXY-PREGNA-3,5-DIEN-20-ONE DIACETATE 17-ACETOXYPREGNENOLONE 20-Oxopregna-5,16-dien-3-β-ylacetat Pregnenolon Hydroxyprogesteron

Downstream Produkte

(3S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-3-sulfooxy-1 Prasteron

3-β,17-α-Dihydroxypregn-5-en-20-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 91)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32360	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006608290; 18621169109	market03@meryer.com	China	40241	62
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3989	66
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15878	55

387-79-1(3-β,17-α-Dihydroxypregn-5-en-20-on)Verwandte Suche:

Pregnenolonacetat Pregnenolon 3-β,21-Dihydroxypregn-5-en-20-ondi(acetat) (20R)-Pregn-5-en-3β,20-diol 3-β,17-α-Dihydroxy-16-β-methylpregn-5-en-20-on

17alpha-Hydroxy
(3b)-3,17-dihydroxy-Pregn-5-en-20-one
17a-Hydroxypregnolone
17ALPHA-LPHA-HYDROXYPREGNENOLONE
5-Pregnen-3b,17-dihydroxy-3-one
3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
17-OH PREG
17-OH Pregnenolone
3β,17-Dihydroxypregn-5-en-20-one
3β,17α-Dihydroxypregn-5-en-20-one
3-beta,17-dihydroxypregn-5-en-20-one
3-beta,17-alpha-dihydroxypregn-5-en-20-one
Hydroxypregnenolone
17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H ASSAY ASSAY CHARACTERISTICS
17ALPHA-LPHA-HYDROXYPREGNENOLONE (1,2-3 H)
17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H RIA KIT ASSAY CHARACTERISTICS
17ALPHA-LPHA-HYDROXYPREGNENOLONE CRYSTALLINE
17α-Hydroxypregnenolone,3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
NSC 63853
3β,17α-Dihydroxy-5-pregnen-20-one
5-Pregnene-3β,17α-diol-20-one
17α-Hydroxypregnenolone solution
17α-hydroxypregnenolone solution,100ppm
3B 17A-DIHYDROXYPREGN-5-EN-20-ONE
3BETA,17ALPHA-DIHYDROXY-DELTA5-PREGNEN-20-ONE
3BETA,17ALPHA-DIHYDROXY-5-PREGNEN-20-ONE
3-BETA,17-DIHYDROXY-5-PREGNEN-3-ONE
5-PREGNENE-3BETA,17ALPHA-DIOL-20-ONE
5-PREGNEN-3-BETA, 17-DIOL-20-ONE
5-PREGNEN-3BETA-17A-DIOL-20-ONE
5-PREGNEN-3BETA,17ALPHA-DIOL-20-ONE
17-dihydroxy-(3-beta)-pregn-5-en-20-on
3-beta,17-dihydroxy-pregn-5-en-20-on
HYDROXYPREGNENOLONE, 17A-
17A-HYDROXYPREGENOLONE
17A-HYDROXY PREGNENOLONE
17ALPHA-HYDROXYPREGNENOLONE
17-HYDROXYPREGNENOLONE
Pregn-5-en-20-one, 3,17-dihydroxy-, (3β)-
17alpha-Hydroxypregnenolone-20,21-13C2,16,16-d2
17α-Hydroxypregnenolone
3b,17-Dihydroxy-5-pregnen-20-one
17α-Hydroxypregnenolone (Solution)
"17A-HYDROXY PREGNENOLONE 13C2,D2"
Inhibitor,17a Hydroxypregnenolone,Endogenous Metabolite,17aHydroxypregnenolone,inhibit,17a-Hydroxypregnenolone
Dronedarone HCl-d6
5-PREGNEN-3β, 17-DIOL-20-ONE
387-79-1
Steroids