Benzolsulfonamid
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- CAS-Nr.
- 98-10-2
- Bezeichnung:
- Benzolsulfonamid
- Englisch Name:
- Benzenesulfonamide
- Synonyma:
- BSA;BENZENESULPHONAMIDE;CL160;mandb7973;benzsulfamide;Benzosuifqnamide;Benzenesulfomide;Benzosulfonamide;benzolsulfonamide;BENZENESULFONAMIDE
- CBNumber:
- CB4200738
- Summenformel:
- C6H7NO2S
- Molgewicht:
- 157.19
- MOL-Datei:
- 98-10-2.mol
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Benzolsulfonamid Eigenschaften
- Schmelzpunkt:
- 149-152 °C (lit.)
- Siedepunkt:
- 315.5±25.0 °C(Predicted)
- Dichte
- 1.274 (estimate)
- Brechungsindex
- 1.5500 (estimate)
- Flammpunkt:
- 250°C
- storage temp.
- Store below +30°C.
- Löslichkeit
- methanol: soluble25mg/mL
- pka
- 10.1(at 25℃)
- Aggregatzustand
- Powder, Crystals and/or Chunks
- Farbe
- White to off-white
- Wasserlöslichkeit
- 4.3 g/L (16 ºC)
- BRN
- 1100566
- InChIKey
- KHBQMWCZKVMBLN-UHFFFAOYSA-N
- CAS Datenbank
- 98-10-2(CAS DataBase Reference)
- NIST chemische Informationen
- Benzenesulfonamide(98-10-2)
- EPA chemische Informationen
- Benzenesulfonamide (98-10-2)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| S-Sätze: |
36 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
DA9380000 |
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| TSCA |
Yes |
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| HS Code |
29350090 |
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| Toxizität |
LD50 orally in Rabbit: 991 mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Benzolsulfonamid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white to off-white granular crystalline powder. insoluble in water, soluble in ethanol and ether. soluble in alkali.
Verwenden
Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. Benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.
synthetische
Benzenesulfonamide is obtained by amination of benzenesulfonyl chloride.
Application
Benzenesulfonamides serve as intermediates in the production of polysulfonamides, which are used as tanning agents and plastics. N- Alkylamides of the benzenesulfonic and tolue-nesulfonic acids can be used as plasticizers. Aminobenzenesulfonamides and diaryldisulfonylamines with amino groups serve as intermediates in the production of azo dyes.
Sicherheitsprofil
Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits very toxic fumes of SOx and NOx.
Properties and Applications
Benzenesulfonamides are readily crystallizing, colorless compounds with defined melting points and poor solubility in water. They are therefore suitable for the characterization of sulfonic acids (via the sulfonyl chlorides) and of primary and secondary amines and for the separation of amine mixtures (Hinsberg method). Benzenesulfonamides are weak acids and form salts with bases. They are thermally stable and very difficult to hydrolyze with alkali; however, they are more easily hydrolyzed with mineral acids. In concentrated sulfuric acid sodium nitrite splits them into sulfonic acids and nitrogen. The hydrogen atoms bound to the nitrogen can be substituted.
Benzolsulfonamid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Benzolsulfonamid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 398)Lieferanten
98-10-2(Benzolsulfonamid)Verwandte Suche:
- BenzenesulfonaMide, 98+% 500GR
- Benzenesulfonamide Vetec(TM) reagent grade, 98%
- Benzenesulfomide
- BENZENESULFONYLAMIDE
- BENZENESULFONAMIDE
- Benzene sulfonamtde
- Benzosuifqnamide
- Benaenesulfonicamide
- benzolsulfonamide
- Benzosulfonamide
- mandb7973
- BENZENESULFONAMIDE, 98+%
- Benzenesulfonamide (7CI,8CI,9CI)
- Benzenesulfonamide(BSA)
- benzenesulfonic amide
- benzsulfamide
- BENZENESULPHOAMIDE
- phenyl sulfonamide
- Benzene sulfonamide, BSA, Benzenesulfonamide
- Benzenesulfonamide >
- BENZENESULFONAMIDE FOR SYNTHESIS
- Benzenesulfonamide ISO 9001：2015 REACH
- Benzenesulfonamide (Benzenesulphonamide, Benzosulfonamide)
- 98-10-2 Benzenesulfonamide
- 4'-Anhydrovinblastine
- CL160
- BENZENESULPHONAMIDE
- BSA
- Benzen Sulphanamide
- Benzene sulphonamide (84%,99.5%)
- Benzenesulfonamide， ≥ 98.0%
- 98-10-2
- 1998-10-2
- 36-07-0
- 1998-10-02
- C6H7N1O2S1
- C6H6NO2S
- C6H5SO2NH2
- C6H7O2NS
- Organic Building Blocks
- Sulfur Compounds
- Sulfonamides/Sulfinamides
- Building Blocks
- Urinary System Agents
- Organic Building Blocks
- Sulfonamides/Sulfinamides
- Sulfur Compounds
- Pharmaceutical Intermediates
- SULFONAMIDE
- Benzene derivatives
- Organics
