(2,5-Dihydroxyphenyl)essigsure
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- CAS-Nr.
- 451-13-8
- Bezeichnung:
- (2,5-Dihydroxyphenyl)essigsure
- Englisch Name:
- HOMOGENTISIC ACID
- Synonyma:
- 2-(2,5-dihydroxyphenyl)acetic acid;alcapton;Melanic acid;homogentisicaci;HOMOGENTISIC ACID;Homogentisinic acid;HOMOGENTISIC ACID(RG);Homogentisic Acid >Homogentisic Acid, ≥ 97.0%;2,5-Dihydroxy-α-toluic acid
- CBNumber:
- CB5207860
- Summenformel:
- C8H8O4
- Molgewicht:
- 168.15
- MOL-Datei:
- 451-13-8.mol
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(2,5-Dihydroxyphenyl)essigsure Eigenschaften
- Schmelzpunkt:
- 150-152 °C (lit.)
- Siedepunkt:
- 257.07°C (rough estimate)
- Dichte
- 1.3037 (rough estimate)
- Brechungsindex
- 1.5090 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- Soluble in methanol.
- pka
- 4.4(at 25℃)
- Aggregatzustand
- crystalline
- Farbe
- off-white to tan
- Wasserlöslichkeit
- very faint turbidity
- Merck
- 14,4737
- BRN
- 2692860
- LogP
- 0.860
- CAS Datenbank
- 451-13-8(CAS DataBase Reference)
- EPA chemische Informationen
- Benzeneacetic acid, 2,5-dihydroxy- (451-13-8)
(2,5-Dihydroxyphenyl)essigsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
off-white to tan crystals or crystalline powder
Verwenden
Homogentisic acid may be used as an analytical reference standard for the quantification of the analyte in the following:
- Urine matrices using reversed-phase liquid chromatography tandem mass spectrometry (LC-MS/MS).
- Strawberry tree honey samples using reversed phase-high performance liquid chromatography (RP-HPLC) and ion chromatography (IC).
It may also be used as an internal standard for the determination of ascorbic acid (AA) and uric acid (UA) in human plasma samples using high-pressure liquid chromatography–electrochemical detection (HPLC–ECD).
Allgemeine Beschreibung
Homogentisic acid (HGA) is an intermediate formed during the catabolism of phenylalanine and tyrosine. Alkaptonuria, a metabolic disorder, is characterized by high levels of HGA in serum and urine due to the deficiency of the enzyme homogentisic acid oxidase, which is involved in the degradation of HGA.
läuterung methode
Crystallise homogentisic acid from EtOH/CHCl3 or H2O (solubility is 85% at 25o). [Beilstein 10 IV 1506.]
(2,5-Dihydroxyphenyl)essigsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(2,5-Dihydroxyphenyl)essigsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 130)Lieferanten
451-13-8((2,5-Dihydroxyphenyl)essigsure)Verwandte Suche:
- (2,5-dihydroxyphenyl)-aceticaci
- 2,5-dihydroxy-benzeneaceticaci
- 2,5-dihydroxybenzeneaceticacid
- alcapton
- Homogentisic acid 2,5-Dihydroxyphenylacetic acid
- homogentisic acid free acid
- Benzeneacetic acid,2,5-dihydroxy-
- HoMogentisic acid crystalline
- HOMOGENTISIC ACID(RG)
- 2,5-Dihydroxy-α-toluic acid
- Homogentisinic acid
- 2,5-Dihydroxyphenylacetic acid,95%
- 2,5-Dihydroxyphenylacetic acid,99%
- 1,4-HYDROQUINONEACETIC ACID
- HOMOGENTISIC ACID
- 2,5-DIHYDROXYPHENYLACETIC ACID
- 2-(2,5-dihydroxyphenyl)acetate
- Homogentisic Acid >
- Melanic acid
- homogentisicaci
- 5-dihydroxy-benzeneaceticaci
- 2,5-Dihydroxyphenylacetic acid, 97%,
- 2-(2,5-dihydroxyphenyl)acetic acid
- Homogentisic Acid, ≥ 97.0%
- 451-13-8
- HO2C6H3CH2COOH
- Metabolomics
- Metabolic Libraries
- Organic Building Blocks
- Building Blocks
- BioChemical
- Amino Acid Library
- C8
- Carbonyl Compounds
- Carboxylic Acids
- Aromatic Phenylacetic Acids and Derivatives
- Aromatics
- Intermediates
