2-AMINO-5-FLUOROACETOPHENONE
|
|
|
- CAS-Nr.
- 2343-25-1
- Englisch Name:
- 2-AMINO-5-FLUOROACETOPHENONE
- Synonyma:
- 1-(2-AMino-5-fluorophenyl)ethanone;1-(2-amino-5-fluorophenyl)ethan-1-one;1-(2-Amino-5-fluorophenyl);2-AMINO-5-FLUOROACETOPHENONE;5-Fluoro-2-Amino-Acetophenone;Ethanone, 1-(2-amino-5-fluorophenyl)-
- CBNumber:
- CB52451184
- Summenformel:
- C8H8FNO
- Molgewicht:
- 153.15
- MOL-Datei:
- 2343-25-1.mol
|
2-AMINO-5-FLUOROACETOPHENONE Eigenschaften
- Schmelzpunkt:
- 64-65 °C
- Siedepunkt:
- 264.2±20.0 °C(Predicted)
- Dichte
- 1.201±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 2.37±0.10(Predicted)
2-AMINO-5-FLUOROACETOPHENONE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
2-Amino-5-fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthese
600 g of 2-ethynyl-4-fluoroaniline and 4 L of water were added to the reaction flask, and then 476 g of hydrochloric acid (concentration: 35%) was added, and thereaction was carried out at 50 ??C for 36 hours.After the reaction, the temperature is lowered to 20-25 ??C, the reaction solution is adjusted to pH 8-9 with 50% sodium hydroxide solution, thetemperature is controlled to not exceed 30 ??C during pH adjustment, and the filter cake is washed with 1 L of water and decompressed at 50 ??C. After drying for 12 h, 622 g of pale yellow solid was obtained, yield91.4%.HPLC purity was 99.2%.
2-AMINO-5-FLUOROACETOPHENONE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-AMINO-5-FLUOROACETOPHENONE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 83)Lieferanten
2343-25-1()Verwandte Suche:
- 1-(2-Amino-5-fluorophenyl)
- 2-AMINO-5-FLUOROACETOPHENONE
- Ethanone, 1-(2-amino-5-fluorophenyl)-
- 1-(2-amino-5-fluorophenyl)ethan-1-one
- 1-(2-AMino-5-fluorophenyl)ethanone
- 5-Fluoro-2-Amino-Acetophenone
- 2343-25-1
