trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide

3854-04-4

CAS-Nr.: 3854-04-4

Englisch Name:: trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide

Synonyma:: CPD3509;Oxotremorine M (iodide);trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide

CBNumber:: CB63387012

Summenformel:: C11H19IN2O

Molgewicht:: 322.19

MOL-Datei:: 3854-04-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 18

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Eigenschaften

storage temp.: Desiccate at -20°C

Löslichkeit: DMSO : 125 mg/mL (387.97 mM; Need ultrasonic)

Aggregatzustand: Powder

Wasserlöslichkeit: Soluble to 100 mM in water

Sicherheit

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Oxotremorine M is a non-selective muscarinic (M) acetylcholine receptor agonist that induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M₂, M₃, and M₂/M₃ knockout mice (EC₅₀s = 0.36, 0.52, 1.62, and 1.48 μM, respectively). It also increases M₄-induced inhibition of calcium currents in NG108-15 mouse neuroblastoma X rat glioma hybrid cells (EC₅₀ = 0.14 μM). Oxotremorine M inhibits KCNQ2/3 potassium currents in Xenopus oocytes expressing M₁ receptors and KCNQ2/3 potassium channels (IC₅₀ = 1.1 μM). It also directly inhibits KCNQ2/3 potassium channels, decreasing KCNQ2/3 potassium currents in Xenopus oocytes lacking muscarinic receptors in a dose-dependent manner.

Verwenden

Oxotremorine M is a muscarinic receptor agonist.

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 18)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3421	58
BOC Sciences	--	info@bocsci.com	USA	0	65
Shanghai hongqu biomedical technology co. LTD	88888888888	hongquchem@qq.com	China	5132	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Zhengzhou Akem Chemical Co., Ltd	13303867194	3001317055@qq.com	China	9421	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223	psaitong@jm-bio.com	China	29834	58
Kaifeng Mingren Pharmaceutical Co.,LTD	0371-65741762	sales@hasunny.com	China	2380	58