Methysergidhydrogenmaleat
|
|
|
- CAS-Nr.
- 129-49-7
- Bezeichnung:
- Methysergidhydrogenmaleat
- Englisch Name:
- METHYSERGIDE MALEATE
- Synonyma:
- sansert;NSC-186061;deseril-retard;Deseril, Sansert;maleate(1:1)(salt);METHYSERGIDE MALEATE;methysergidedimaleate;methysergidebimaleate;Methysergide Maleate, USP;methysergide maleate salt
- CBNumber:
- CB8753434
- Summenformel:
- C25H31N3O6
- Molgewicht:
- 469.54
- MOL-Datei:
- 129-49-7.mol
|
Methysergidhydrogenmaleat Eigenschaften
- storage temp.
- Store at RT
- Löslichkeit
- DMSO: >10 mg/mL
- Aggregatzustand
- solid
- Farbe
- white to off-white
- Wasserlöslichkeit
- Soluble to 10 mM in water with gentle warming
- Stabilität:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
T |
|
|
| R-Sätze: |
25 |
|
|
| S-Sätze: |
45 |
|
|
| RIDADR |
UN 2811 6.1/PG 3 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
KE5410000 |
|
|
| HazardClass |
6.1(b) |
|
|
| PackingGroup |
III |
|
|
| HS Code |
2939690000 |
|
|
| Toxizität |
mouse,LD50,intravenous,185mg/kg (185mg/kg),"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 101, 1972. |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
|
| Sicherheit |
|
Methysergidhydrogenmaleat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
S-Sätze Betriebsanweisung:
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Verwenden
Methysergide maleate salt has been used as a serotonin (5HT) receptor antagonist to evaluate the potential systemic effects of methysergide (METH) and 5-HT infusions on production and milk composition in multiparous Holstein cows. It may also be used as a serotonin receptor blocker to identify the serotonergic receptor type involved in the direct excitation of mitral cells in the main olfactory bulb.
Biologische Aktivität
Mixed 5-HT 1 /5-HT 2 receptor antagonist.
Sicherheitsprofil
Poison by ingestion and
intravenous routes. Experimental
reproductive effects. Human mutation effects reported. When heated to
decomposition it emits toxic fumes of NOx.
Methysergidhydrogenmaleat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methysergidhydrogenmaleat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 51)Lieferanten
129-49-7(Methysergidhydrogenmaleat)Verwandte Suche:
- 1-(hydroxymethyl)propylamideof1-methyl-(+)-lysergicacidhydrogenmaleate
- deseril-retard
- ergoline-8-beta-carboxamide,9,10-didehydro-n-(1-(hydroxymethyl)propyl)-1,6-dim
- maleate(1:1)(salt)
- Methysergide Maleate, USP
- Methysergide Maleate (350 mg)
- methysergidebimaleate
- methysergidedimaleate
- methysergidehydrogenmaleate
- n-((1-hydroxymethyl)propyl)-1-methyl-lysergamidmaleate
- sansert
- [8B(S)]-9,10-DIDEHYDRO-N-[1-(HYDROXYMETHYL)PROPYL]-1,6-DIMETHYLERGOLINE-8-CARBOXAMIDE MALEATE
- METHYSERGIDE MALEATE
- METHYLSERGIDE MALEATE SALT
- METHYSERGIDE MALEATE SEROTONIN ANTAGONIS T
- methysergide maleate salt
- [8beta(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate
- NSC-186061
- [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamidemaleate
- LWYXFDXUMVEZKS-ZVFOLQIPSA-N
- Methysergide Maleate (1440003)
- Deseril, Sansert
- Ergoline-8-carboxamide,9,10-didehydro-N-[(1S)-1-(hydroxymethyl)propyl]-1,6-dimethyl-, (8b)-,(2Z)-2-butenedioate (1:1) (salt)
- 129-49-7
- C21H27N3O2C4H4O4
- Antagonists
- Neurotransmitters
- Serotonergics
- Serotonin receptor
- ATRAVET
