Haematoporphyrindihydrochlorid
|
|
|
- CAS-Nr.
- 17696-69-4
- Bezeichnung:
- Haematoporphyrindihydrochlorid
- Englisch Name:
- HEMATOPORPHYRIN DIHYDROCHLORIDE
- Synonyma:
- ematoporfirina;Hemaloporphyrin;HematoporphyrineDihcl;HAEMATOPORPHYRINDICHLORIDE;Haematopophyrin dihydrochloride;HEMATOPORPHYRIN DIHYDROCHLORIDE;HAEMATOPORPHYRIN DIHYDROCHLORIDE;HEMATOPORPHYRIN IX DIHYDROCHLORIDE;HAEMATOPORPHYRIN Dihydrochloride(RG);HEMATOPORPHYRIN DIHYDROCHLORIDE USP/EP/BP
- CBNumber:
- CB9281835
- Summenformel:
- C34H39ClN4O6
- Molgewicht:
- 635.16
- MOL-Datei:
- 17696-69-4.mol
|
Haematoporphyrindihydrochlorid Eigenschaften
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- Very Dark Red
- Wasserlöslichkeit
- Insoluble in water. Soluble in pyridine (5%).
- Merck
- 14,4636
- BRN
- 78957
- Stabilität:
- Hygroscopic
- EPA chemische Informationen
- 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, dihydrochloride (17696-69-4)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| R-Sätze: |
33 |
|
|
| RTECS-Nr. |
TS5505000 |
|
|
| TSCA |
Yes |
|
|
| Toxizität |
mouse,LD50,intraperitoneal,169mg/kg (169mg/kg),BEHAVIORAL: TREMORBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY),Bollettino Chimico Farmaceutico. Vol. 117, Pg. 145, 1978. |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
|
Haematoporphyrindihydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R33:Gefahr kumulativer Wirkungen.
Beschreibung
Hematoporphyrin is a photosensitizer. Hematoporphyrin (3 μM) increases oxygen consumption and decreases the respiratory control ratio (RCR) in irradiated isolated rat liver mitochondria. It induces DNA breaks in cell-free assays, but not in human HeLa cervical cancer cells, in a light-dependent manner when used at a concentration of 6 μM. Hematoporphyrin (12 μM) decreases the survival of irradiated, but not non-irradiated, HeLa cells. Hematoporphyrin (5 mg/kg) decreases growth of subcutaneous Yoshida AH-130 hepatoma tumors in rats when administered with radiation.
Verwenden
Endogenous porphyrin formed by the acid hydrolysis of hemoglobin. It is employed as an active pharmaceutical intermediate.
Haematoporphyrindihydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Haematoporphyrindihydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 123)Lieferanten
17696-69-4(Haematoporphyrindihydrochlorid)Verwandte Suche:
Mercaptaminhydrochlorid
Triethylammoniumchlorid
2,2'-Azobis(2-methylpropion-amidin)dihydrochlorid
N-2-Aminoethyl-1-naphthylamindihydrochlorid
2-Aminoethylammoniumchlorid
Dimethylammoniumchlorid
Haematoporphyrin
4-Pentensäure
Pent-3-en-2-ol
21H,23H-Porphin
Haematoporphyrindihydrochlorid
3-Methyl-3-buten-2-ol
7,12-Diethyl-3,8,13,17-tetramethyl-21H,23H-porphin-2,18-dipropionsure
7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphin-2,18-dipropionsurehydrochlorid
3,7,12,17-Tetramethyl-21H,23H-porphin-2,18-dipropionsuredihydrochlorid
- 21h,23h-porphine-2,18-dipropanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-tetr
- 21h,23h-porphine-2,18-propanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-tetr
- 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-2,18-porphinedipropionicacid
- acido1,3,5,8-tetrametil-2,4-bis(idrossietil)porpfina-6,7-dipropionicodiclor
- ematoporfirina
- HEMATOPORPHYRIN IX DIHYDROCHLORIDE
- HEMATOPORPHYRIN DIHYDROCHLORIDE
- HAEMATOPORPHYRIN DIHYDROCHLORIDE
- 8,13-BIS(1-HYDROXYETHYL)-3,7,12,17-TETRAMETHYL-21H,23H-PORPHINE-2,18-DIPROPIONIC ACID DIHYDROCHLORIDE
- Haematopophyrin dihydrochloride
- HematoporphyrineDihcl
- Hemaloporphyrin
- HAEMATOPORPHYRIN Dihydrochloride(RG)
- HAEMATOPORPHYRINDICHLORIDE
- 7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid hydrochloride
- 8,13-Bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid dihydrochloride
- HematoporphyrinIXdihydrochloride,8,13-Bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionicaciddihydrochloride
- HEMATOPORPHYRIN DIHYDROCHLORIDE USP/EP/BP
- 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, hydrochloride (1:2)
- 3,3'-(7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethylporphyrin-2,18-diyl)dipropionic acid dihydrochloride
- 3,3'-(7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethylporphyrin-2,18-diyl)dipropionic acid dihydrochloride
- 17696-69-4
- C34H38N4O62HCl
- C34H40Cl2N4O6
- C34H38N4O6HCl
- C34H38N4O62ClH
- Porphyrins
- Natural Porphyrins and Derivitives
- Porphyrins
- Biochemistry
- Miscellaneous Biochemicals
- porphine (porphyrin) ligand
