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Fluoroiodomethane

CAS No.
373-53-5
Chemical Name:
Fluoroiodomethane
Synonyms
Fluoromethyl iodide;Fluor(iod)methan;fluoro-iodo-methane;Fluoroiodomethane 95%;Methane, fluoroiodo- (6CI,8CI,9CI);Fluoroiodomethane (ca. 2mol/L in Acetonitrile)
CBNumber:
CB01512724
Molecular Formula:
CH2FI
Molecular Weight:
159.93
MDL Number:
MFCD12404952
MOL File:
373-53-5.mol
Last updated:2024-01-09 09:44:15

Fluoroiodomethane Properties

Boiling point 53.4℃
Density 2.366 g/cm3 (20 ºC)
refractive index 1.491 (589.3 nm 20℃)
form clear liquid
color Colorless to Light yellow
Stability Volatile
InChI InChI=1S/CH2FI/c2-1-3/h1H2
InChIKey XGVXNTVBGYLJIR-UHFFFAOYSA-N
SMILES C(F)I
CAS DataBase Reference 373-53-5
FDA UNII F4DZ382EN9

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H319-H335-H301+H311+H331-H315
Precautionary statements  P260-P280-P312
HS Code  2903798000
NFPA 704
2
3 0

Fluoroiodomethane price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F1279 Fluoroiodomethane (ca. 2mol/L in Acetonitrile) 373-53-5 5ML $252 2024-03-01 Buy
TRC F591955 Fluoroiodomethane 373-53-5 10g $1065 2021-12-16 Buy
SynQuest Laboratories 1100-K-01 Fluoroiodomethane 95% 373-53-5 1g $165 2021-12-16 Buy
AK Scientific 0662CV Fluoroiodomethane 373-53-5 5ml $347 2021-12-16 Buy
SynQuest Laboratories 1100-K-01 Fluoroiodomethane 95% 373-53-5 5G $495 2021-12-16 Buy
Product number Packaging Price Buy
F1279 5ML $252 Buy
F591955 10g $1065 Buy
1100-K-01 1g $165 Buy
0662CV 5ml $347 Buy
1100-K-01 5G $495 Buy

Fluoroiodomethane Chemical Properties,Uses,Production

Uses

Fluoroiodomethane is an synthetic precursor for the fluoromethylation of radiopharmaceuticals.

Properties and Applications

Fluoroiodomethane is a commercially available liquid with a boiling point of 53.4 °C. This reagent is easy to handle and represents a non-ozone-depleting alternative to the frequently used CFC (chlorofluorocarbons) and HBFC (hydrobromofluorocarbons). This reagent is featured by two carbon–halogen bonds (C–I and C–F) characterized by diverse reactivity. The bond dissociation energy (BDE) of C–I (233 kJ mol?1) compared to that of the C–F bond (460 kJ mol?1) enables a selective activation of CH2FI for multiple pathways delivering the fluoromethyl fragment unit. Indeed, the C–I bond can be engaged in lithium exchange protocols, transition-metal catalyzed reactions, nucleophilic substitutions, and radical pathways[1].

References

[1] Marco Colella . “The synthetic versatility of fluoroiodomethane: recent applications as monofluoromethylation platform.” Organic Biomolecular Chemistry 20 23 (2022): Pages 4669-4680.

593-70-4
373-53-5
Synthesis of Fluoroiodomethane from Chlorofluoromethane
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LEAPCHEM CO., LTD.
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  • Jan 9,2024

View Lastest Price from Fluoroiodomethane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
fluoro-iodo-methane pictures 2023-12-29 fluoro-iodo-methane
373-53-5
US $101.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
fluoro-iodo-methane Fluoroiodomethane 95% Methane, fluoroiodo- (6CI,8CI,9CI) Fluoroiodomethane (ca. 2mol/L in Acetonitrile) Fluoromethyl iodide Fluor(iod)methan 373-53-5 CH2FI