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7-Chloro-4-quinolinamine

7-Chloro-4-quinolinamine structure

CAS No.: 1198-40-9

Chemical Name:: 7-Chloro-4-quinolinamine

Synonyms: BUTTPARK 22\09-04;7-chloro-4-quinolinamine;7-chloro-4-aminoquinoline;4-AMINO-7-CHLOROQUINOLINE;4-QuinolinaMine,7-chloro-;(7-chloro-4-quinolyl)amine;7-CHLORO-QUINOLIN-4-YLAMINE;Hydroxychloroquine Impurity 34;4-amino-7-chloroQUINOLINE:7-chloro-4-quinolinamine

CBNumber:: CB0199827

Molecular Formula:: C9H7ClN2

Molecular Weight:: 178.62

MDL Number:: MFCD00828822

MOL File:: 1198-40-9.mol

MSDS File:: SDS

Last updated:2023-05-04 17:34:32

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7-Chloro-4-quinolinamine Properties

Melting point	150-152.5 °C
Boiling point	366.8±27.0 °C(Predicted)
Density	1.363±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	solid
pka	7.49±0.50(Predicted)
color	Off-white
CAS DataBase Reference	1198-40-9(CAS DataBase Reference)
FDA UNII	2SJ6Y866TU

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301-H319
Precautionary statements	P301+P310+P330-P305+P351+P338
Hazard Codes	T
Risk Statements	25-36
Safety Statements	26-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
HS Code	2933499090

7-Chloro-4-quinolinamine price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	BBO000159	4-Amino-7-chloroquinoline Aldrich	1198-40-9	1g	$320	2024-03-01	Buy
TRC	C422285	7-Chloroquinolin-4-amine	1198-40-9	1g	$415	2021-12-16	Buy
TRC	C422285	7-Chloroquinolin-4-amine	1198-40-9	250mg	$165	2021-12-16	Buy
Apolloscientific	OR307952	4-Amino-7-chloroquinoline	1198-40-9	1g	$185	2021-12-16	Buy
Biosynth Carbosynth	FC43495	7-Chloroquinolin-4-amine	1198-40-9	1g	$220	2021-12-16	Buy

Product number	Packaging	Price	Buy
BBO000159	1g	$320	Buy
C422285	1g	$415	Buy
C422285	250mg	$165	Buy
OR307952	1g	$185	Buy
FC43495	1g	$220	Buy

7-Chloro-4-quinolinamine Chemical Properties,Uses,Production

Uses

7-Chloroquinolin-4-amine is an aminoquinoline that complexes ferriprotoporphyrin IX (Fe(III)PPIX) and inhibits its conversion to β-hematin (hemozoin).

Definition

ChEBI: 4-Amino-7-chloroquinoline is an aminoquinoline.

Synthesis Reference(s)

Journal of the American Chemical Society, 69, p. 704, 1947 DOI: 10.1021/ja01195a501

Synthesis

4-amino-7-chloroquinoline is obtained byreacting 7-chloro-4-hydrazinoquinoline ,sodium borohydride with nickel (II) chloride hexahydrate in methanol.To a suspension of 7-chloro-4-hydrazinoquinoline (1.67 g, 8.6 mmol) and nickel (II) chloride hexahydrate (2.00 g, 8.6 mmol) in methanol (33 ml), sodium borohydride (0.98 g, 25.8 mmol) was added cautiously while stirring the reaction mixture vigorously at room temperature and left to react overnight. The reaction mixture was filtered through celite pad. Water was used to dilute the filtrate layer and then washed with ethyl acetate. The organic layer was dried with magnesium sulphate and concentrated in vacuo to give the title compound as a yellow powder (1.09 g, 72%): mp: 143 – 147 ℃ (Lit.: 147 – 148 ℃) ;
vmax/cm-1 3337 s (N-H), 1642 m (C=N), 1609 m and 1575 m (C=N); δH (300 MHz; DMSO-d6) 8.28 (1H, d, J 5.3, C(2)H), 8.19 (1H, d, J 9.1, C(5)H), 7.76 (1H, d, J 1.6, C(8)H), 7.39 (1H, dd, J 9.1, 1.6, C(6)H), 7.03 (2H, s, NH2), 6.57 (1H, d, J 5.3, C(3)H); δC (75 MHz; DMSO-d6) 152.0 (Ar-C), 151.1 (C(2)H), 148.9 (Ar-C), 133.7 (Ar-C), 126.8 (C(8)H), 124.8 (C(5)H), 123.9 (C(6)H), 117.0 (Ar-C), 102.7 (C(3)H); m/z (-ES) 179 (100%, [M+H]- with 35Cl), 181 (35%, [M+H]- with 37Cl); found by +ES 179.0377, C9H8ClN2 ([M+H]+ with 35Cl), requires 179.0371, error 3.3 ppm.

7-Chloro-4-quinolinamine Preparation Products And Raw materials

Raw materials

Preparation Products

7-Chloro-4-quinolinamine Suppliers

Global( 94)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9346	55
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12568	58
Shanghai kingmorn biotechnology Co.,Ltd.	021-62200788 15000569291	2199306478@qq.com	CHINA	100	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503259 +86-19930503259	cherry@crovellbio.com	China	18455	58
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	sales@anbuchem.com	China	3000	58

Supplier	Advantage
Hangzhou FandaChem Co.,Ltd.	55
Nanjing Dolon Biotechnology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Shanghai kingmorn biotechnology Co.,Ltd.	58
Nextpeptide Inc	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Zhengzhou Anbu Chem Co.,Ltd	58

View Lastest Price from 7-Chloro-4-quinolinamine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-12	7-Chloro-4-quinolinamine 1198-40-9	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-16	7-Chloro-4-quinolinamine 1198-40-9	US $0.00 / g	10g	99%	>100kg	Shanghai kingmorn biotechnology Co.,LTD.
2020-01-10	7-Chloro-4-quinolinamine 1198-40-9	US $1.00 / g	1g	99.0%	100kg	Career Henan Chemical Co

7-Chloro-4-quinolinamine
1198-40-9
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

7-Chloro-4-quinolinamine
1198-40-9
US $0.00 / g
99%
Shanghai kingmorn biotechnology Co.,LTD.

7-Chloro-4-quinolinamine
1198-40-9
US $1.00 / g
99.0%
Career Henan Chemical Co

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BUTTPARK 22\09-04 7-chloro-4-aminoquinoline 4-amino-7-chloroQUINOLINE:7-chloro-4-quinolinamine (7-chloro-4-quinolyl)amine 4-QuinolinaMine,7-chloro- 4-AMINO-7-CHLOROQUINOLINE 7-CHLORO-QUINOLIN-4-YLAMINE 7-chloro-4-quinolinamine Hydroxychloroquine Impurity 34 1198-40-9 pharmacetical