ChemicalBook >> CAS DataBase List >>KF31327
KF31327
- CAS No.
- 220060-39-9
- Chemical Name:
- KF31327
- Synonyms
- KF31327;Thioquinapiperfil;KF-31327 free base;Thioquinapiperifil;3-ethyl-8-[[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylamino]-1H-imidazo[4,5-g]quinazoline-2-thione;2H-Imidazo[4,5-g]quinazoline-2-thione, 3-ethyl-1,3-dihydro-8-[[[2-[4-(hydroxymethyl)-1-piperidinyl]phenyl]methyl]amino]-
- CBNumber:
- CB02104148
- Molecular Formula:
- C24H28N6OS
- Molecular Weight:
- 448.58
- MDL Number:
- MFCD11977835
- MOL File:
- 220060-39-9.mol
Last updated:2023-03-13 11:54:01
| FDA UNII | 91GSL5I3VO |
|---|
KF31327 Chemical Properties,Uses,Production
Biological Activity
Thioquinapiperifil (KF31327 free base) is a potent, selective, and noncompetitive inhibitor of phosphodiesterase (PDE-5) (IC50 of 0.074 nM) for sexual maturation studies.
in vitro
Thioquinapiperifil can be found in dietary supplements. Thioquinapiperifil (KF31327 free base) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil (KF31327 free base) are required to inhibit platelet aggregation.
target
| PDE5 0.074 nM (IC 50 ) | PDE1 380 nM (IC 50 ) | PDE2 670 nM (IC 50 ) | PDE3 38 nM ( IC 50 ) | PDE4 800 nM (IC 50 ) |
KF31327 Preparation Products And Raw materials
Raw materials
Preparation Products
KF31327 Suppliers
Global( 19)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Wuhan Greenkj Pharmaceutical Technology Co., Ltd. | 15608630565 | greenkjpharm@163.com | China | 130 | 58 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | wxf@sungening.com | China | 9506 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55827 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 31163 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
220060-39-9(KF31327)Related Search:
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Propoxyphenyl ThiohoMosidenafil
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1of4
KF31327
3-ethyl-8-[[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylamino]-1H-imidazo[4,5-g]quinazoline-2-thione
Thioquinapiperifil
2H-Imidazo[4,5-g]quinazoline-2-thione, 3-ethyl-1,3-dihydro-8-[[[2-[4-(hydroxymethyl)-1-piperidinyl]phenyl]methyl]amino]-
KF-31327 free base
Thioquinapiperfil
220060-39-9
C24H28N6OS