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Glesatinib
- CAS No.
- 936694-12-1
- Chemical Name:
- Glesatinib
- Synonyms
- Glesatinib;Glesatinib (MGCD-265;Benzeneacetamide, 4-fluoro-N-[[[3-fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]amino]thioxomethyl]-
- CBNumber:
- CB03154991
- Molecular Formula:
- C31H27F2N5O3S2
- Molecular Weight:
- 619.7
- MDL Number:
- MFCD30532644
- MOL File:
- 936694-12-1.mol
Last updated:2023-05-15 10:43:12
| Density | 1.380±0.06 g/cm3(Predicted) |
|---|---|
| pka | 9.47±0.70(Predicted) |
| FDA UNII | 7Q29OXD98N |
| NCI Drug Dictionary | glesatinib |
Glesatinib Chemical Properties,Uses,Production
Description
Glesatinib is a TKI that targets tumors with MET and AXL alterations.
Uses
Glesatinib exhibits anti-tumor activity in lung cancer models and patients harboring MET exon 14 mutations and overcomes mutation-mediated resistance.
Clinical Use
Nonclinical models have shown glesatinib to be effective in MET exon 14 skipping mutations. It is currently being evaluated in phase II trials in NSCLC patients with MET alterations.
Glesatinib Preparation Products And Raw materials
Raw materials
Preparation Products
Glesatinib Suppliers
Global( 11)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Shanghai BetterBioChem Co., Ltd. | +86-18017644823 | sales@betterbiochem.com | China | 325 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2492 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4209 | 58 |
| https://hanhongsci.com/ | 021-54306202 18917919676 | info@hanhongsci.com | China | 29989 | 58 |
| Sichuan Yiyan Pharmaceutical Research | 19949968070 | 2904199885@qq.com | China | 919 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9180 | 58 |
Glesatinib
Glesatinib
(MGCD-265
Benzeneacetamide, 4-fluoro-N-[[[3-fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]amino]thioxomethyl]-
936694-12-1
C31H27F2N5O3S2