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2-Hydroxy-4-(trifluoromethyl)quinoline

2-Hydroxy-4-(trifluoromethyl)quinoline Structure
2-Hydroxy-4-(trifluoromethyl)quinoline structure
CAS No.
25199-84-2
Chemical Name:
2-Hydroxy-4-(trifluoromethyl)quinoline
Synonyms
BUTTPARK 33\04-80;4-(Trifluoromethyl)quinolin-2-ol;4-Trifluoromethyl-1H-quinolin-2-one;4-trifluoroMethyl-2(1H)-quinolinone;4-(trifluoromethyl)quinolin-2(1H)-one;2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE;4--(TrifluoroMethyl)quinoline-2(H)-one;2-hydroxy-4-(trifluoroMethyl)quinqline;4-Trifluoromethyl-2(1H)-quinolinone,97%;2(1H)-Quinolinone, 4-(trifluoromethyl)-
CBNumber:
CB0496696
Molecular Formula:
C10H6F3NO
Molecular Weight:
213.16
MDL Number:
MFCD03407380
MOL File:
25199-84-2.mol
MSDS File:
SDS
Last updated:2024-01-18 08:48:14
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2-Hydroxy-4-(trifluoromethyl)quinoline Properties

Melting point >240°C
Boiling point 284 ºC
Density 1.391
Flash point 126 ºC
storage temp. Sealed in dry,Room Temperature
form Solid
color White
InChI InChI=1S/C10H6F3NO/c11-10(12,13)7-5-9(15)14-8-4-2-1-3-6(7)8/h1-5H,(H,14,15)
InChIKey UUROBWTVZZNDFD-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2)C(C(F)(F)F)=CC1=O
CAS DataBase Reference 25199-84-2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Safety Statements  24/25
HS Code  29339900
NFPA 704
1
2 0

2-Hydroxy-4-(trifluoromethyl)quinoline price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H61732 4-Trifluoromethyl-2(1H)-quinolinone, 97% 25199-84-2 1g $264 2024-03-01 Buy
Alfa Aesar H61732 4-Trifluoromethyl-2(1H)-quinolinone, 97% 25199-84-2 250mg $92.2 2023-06-20 Buy
TRC T900055 4-(trifluoromethyl)quinolin-2(1H)-one 25199-84-2 50mg $90 2021-12-16 Buy
Matrix Scientific 074152 2-Hydroxy-4-(trifluoromethyl)quinoline 95+% 25199-84-2 1g $416 2021-12-16 Buy
Medical Isotopes, Inc. 37718 2-Hydroxy-4-(trifluoromethyl)quinoline 95+% 25199-84-2 1g $447 2021-12-16 Buy
Product number Packaging Price Buy
H61732 1g $264 Buy
H61732 250mg $92.2 Buy
T900055 50mg $90 Buy
074152 1g $416 Buy
37718 1g $447 Buy

2-Hydroxy-4-(trifluoromethyl)quinoline Chemical Properties,Uses,Production

Chemical Properties

White solid

Synthesis

4-Trifluoromethylquinolin-2(1H)-one was prepared by reacting aniline and ethyl-4,4,4-trifluoroacetoacetate stirred in toluene.
Experimental Procedure: In a 1 L round flask fitted with a reflux condenser a mixture of 25.60 g aniline, 50.0 g ethyl-4,4,4-trifluoroacetoacetate 300 ml toluene was heated to reflux in an oil bath at 130 °C. After 20 min 3 ml water was added and the mixture was heated at reflux for another 24 h. the reaction mixture was cooled to room temperature and concentrated under reduced pressure. A round flask with 200 mL H2SO4 was heated to 80°C and the crude oil from the step before was added in portions to the H2SO4 keeping the internal temperature below 90°C, total addition time was approximately 40 min. After addition was complete, the mixture was stirred at 80°C for 1 h, cooled and poured onto 400 g crushed ice. The resulting solids were filtered, washed with water, and dried under vacuum at 40°C to give 33.0 g (50%) product (2-Hydroxy-4-(trifluoromethyl)quinoline) as a colorless solid.

2-Hydroxy-4-(trifluoromethyl)quinoline synthesis

62-53-3
372-31-6
25199-84-2
Synthesis of 2-Hydroxy-4-(trifluoromethyl)quinoline from Aniline and Ethyl 4,4,4-trifluoroacetoacetate

2-Hydroxy-4-(trifluoromethyl)quinoline Preparation Products And Raw materials

Raw materials

Ethyl 4,4,4-trifluoroacetoacetate 4-Fluoroaniline Sulfuric acid 4,4,4-trifluoro-3-oxo-N-phenylbutanamide Aniline

Preparation Products

2-Hydroxy-4-(trifluoromethyl)quinoline Suppliers

Global( 117)Suppliers
Supplier Tel Email Country ProdList Advantage
Hongxiong
+undefined18915499068 Suzhouhongxiong@163.com China 120 58
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10828 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81148696 +8615536356810 1047@dideu.com China 3255 58
Supplier Advantage
Hongxiong
58
Hangzhou FandaChem Co.,Ltd. 		55
career henan chemical co 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Shaanxi Dideu Medichem Co. Ltd 		58

View Lastest Price from 2-Hydroxy-4-(trifluoromethyl)quinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE pictures 2022-03-09 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
25199-84-2
 US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE pictures 2020-04-30 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
25199-84-2
 US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE pictures 2019-07-06 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
25199-84-2
 US $1.00 / kg 1kg 98% 200KG Career Henan Chemical Co

25199-84-2(2-Hydroxy-4-(trifluoromethyl)quinoline)Related Search:

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ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 5,7-DICHLORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ACID

1of4

BUTTPARK 33\04-80 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE 4-(Trifluoromethyl)quinolin-2-ol 4-Trifluoromethyl-1H-quinolin-2-one 2-Hydroxy-4-(trifluoromethyl)quinoline ,98% 4-(trifluoromethyl)quinolin-2(1H)-one 2-hydroxy-4-(trifluoroMethyl)quinqline 4--(TrifluoroMethyl)quinoline-2(H)-one 4-trifluoroMethyl-2(1H)-quinolinone 2(1H)-Quinolinone, 4-(trifluoromethyl)- 4-Trifluoromethyl-2(1H)-quinolinone,97% 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE ISO 9001：2015 REACH 25199-84-2 C10H6F3NO