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PPADS TETRASODIUM SALT

CAS No.
192575-19-2
Chemical Name:
PPADS TETRASODIUM SALT
Synonyms
PPADS;PPADS Tetrasodium;4'-disulfonic acid;PPADS (sodium salt);PPADS TETRASODIUM SALT;PPADS tetrasodium salt hydrate;PPADS tetrasodium salt, anhydrous;Pyridoxalphosphate-6-azophenyl-2';pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni;PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID 4NA
CBNumber:
CB0758079
Molecular Formula:
C14H15N3NaO12PS2
Molecular Weight:
535.37
MDL Number:
MFCD00153865
MOL File:
192575-19-2.mol
Last updated:2023-06-30 15:45:59

PPADS TETRASODIUM SALT Properties

storage temp. −20°C
solubility H2O: >10 mg/mL
form solid
color red to orange
Water Solubility Soluble to 100 mM in water
Stability Unstable in Aqueous Solution

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Safety Statements  22-24/25
WGK Germany  3
NFPA 704
0
2 0

PPADS TETRASODIUM SALT price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P178 Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC) 192575-19-2 10mg $100 2024-03-01 Buy
Sigma-Aldrich P178 Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC) 192575-19-2 50mg $234.6 2024-03-01 Buy
Cayman Chemical 14537 PPADS (sodium salt) ≥95% 192575-19-2 10mg $44 2024-03-01 Buy
Cayman Chemical 14537 PPADS (sodium salt) ≥95% 192575-19-2 50mg $183 2024-03-01 Buy
Sigma-Aldrich P178 Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate solid, ≥98% (HPLC) 192575-19-2 250mg $1610 2023-06-20 Buy
Product number Packaging Price Buy
P178 10mg $100 Buy
P178 50mg $234.6 Buy
14537 10mg $44 Buy
14537 50mg $183 Buy
P178 250mg $1610 Buy

PPADS TETRASODIUM SALT Chemical Properties,Uses,Production

Uses

PPADS Tetrasodium is an non-selective purinergic antagonists of P2 ATP receptors. PPADS Tetrasodium is also a potential neuroprotective agents for the treatment of autoimmune and demyelinating disease.

Uses

P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large variety of excitatory postsynaptic responses including fast transmission at central synapses, contraction of smooth muscle cells, platelet aggregation, macrophage activation, and apoptosis. PPADS is a non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50s = 1-2.6 μM), native P2Y2-like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors. PPADS antagonism of ATP-sensitive P2 receptors produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats.

Uses

PPADS Tetrasodium is an non-selective purinergic antagonists of P2 ATP receptors. PPADS Tetrasodium is also a potential neuroprotective agents for the treatment of autoimmune and demyelinating disease .

Definition

ChEBI: Tetrasodium 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate is an organic sodium salt that is the tetrasodium salt of 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid It has a role as a purinergic receptor P2X antagonist. It is an organic sodium salt and an organosulfonate salt. It contains a 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate.

storage

-20°C (desiccate)

PPADS TETRASODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

PPADS TETRASODIUM SALT Suppliers

Global( 46)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3421 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55791 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Absin Bioscience Inc. 021-38015121 15000105423 chenjw@absin.cn China 24734 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58

192575-19-2(PPADS TETRASODIUM SALT)Related Search:

PPADS Tetrasodium PPADS tetrasodium salt, anhydrous PPADS (sodium salt) PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULFONIC ACID TETRASODIUM SALT PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID 4NA PYRIDOXAL-PHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID TETRASODIUM PPADS pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni PYRIDOXAL-PHOSPHATE-6-AZOPHENYL-2',4'-DI -SULPHONIC ACID TETRAS PPADS hydrate tetrasodium salt, 4-[[4-Formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]azo]-1,3-benzenedisulfonic acid tetrasodium salt Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) hydrate tetrasodium salt 4-[[4-FORMYL-5-HYDROXY-6-METHYL-3-[(PHOSPHONOOXY)METHYL]-2-PYRIDINYL]AZO]-1,3-BENZENEDISULFONIC ACID TETRASODIUM PPADS tetrasodium salt hydrate Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate PPADS TETRASODIUM SALT 4-[(2E)-2-[4-formyl-6-methyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-ylidene]hydrazinyl]benzene-1,3-disulfonate 4'-disulfonic acid Pyridoxalphosphate-6-azophenyl-2' 192575-19-2 C14H10N3Na4O12PS2 Adenosines/P2 Nucleotide Receptor - Antagonists Adenosines/P2 Nucleotide Receptors (Purinergics) GPCR Modulators GPCR Proteins Ligand-Gated Ion Channels Membrane Protein Biology Tools Modulators and Antibodies P2X Receptor Modulators Proteins and Derivatives Aldehydes Antagonists Bioactive Small Molecules Biochemicals and Reagents Building Blocks C13-C60 Carbonyl Compounds Cell Biology Cell Signaling and Neuroscience Chemical Synthesis Ion Channels Neuroscience Neurotransmission Neurotransmitters Organic Building Blocks P