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propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate

CAS No.
1421-14-3
Chemical Name:
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
Synonyms
Epontol;WH-5668;TH-2180;FBA-1420;BAY-1420;Fabantol;Fabontal;Sombrevin;propanidid;Bayer-1420
CBNumber:
CB0875008
Molecular Formula:
C18H27NO5
Molecular Weight:
337.41
MDL Number:
MOL File:
1421-14-3.mol
Last updated:2024-03-19 15:37:51

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Properties

Boiling point bp0.7 210-212°
Density 1.2043 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. Refrigerator
solubility DMSO (Slightly), Ethyl Acetate (Slightly)
form Oil
color Pale Yellow to Yellow
FDA UNII AO82L471NS
ATC code N01AX04
EPA Substance Registry System Propanidid (1421-14-3)

SAFETY

Risk and Safety Statements

Toxicity LD50 orally in rats: >10,000 mg/kg (Goldenthal)

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC S676765 Sombrevin 1421-14-3 25mg $85 2021-12-16 Buy
American Custom Chemicals Corporation API0015482 PROPANIDID 95.00% 1421-14-3 5MG $502.28 2021-12-16 Buy
Medical Isotopes, Inc. 61759 Sombrevin 1421-14-3 5G $2200 2021-12-16 Buy
American Custom Chemicals Corporation API0015482 PROPANIDID 95.00% 1421-14-3 25G $5649 2021-12-16 Buy
Product number Packaging Price Buy
S676765 25mg $85 Buy
API0015482 5MG $502.28 Buy
61759 5G $2200 Buy
API0015482 25G $5649 Buy

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Chemical Properties,Uses,Production

Chemical Properties

yellow oil bp0.7 210-212°C soluble in alcohol, chloroform, essentially water insoluble anasthetic Epontol (Bayer) Sombrevin

Uses

Sombrevin, is an ultra short-acting phenylacetate general anesthetic.

Uses

Anesthetic (intravenous).

Definition

ChEBI: Propanidid is a member of methoxybenzenes.

brand name

Epontol (Farbenfabriken Bayer A.G., Germany).

Clinical Use

Propanidid is used as a very short- to shortacting intravenous anesthetic for minor surgery and gynecology. It is characterized by rapid onset of and quick recovery from anesthesia, producing surgical anesthesia for 3 – 4 min. Repeated injections can be used to prolong the anesthesia. Postanesthetic sleep does not occur because the propyl ester is hydrolyzed rapidly in the patient to form inactive 3-methoxy-4- (N,N-diethylcarbamoylmethoxy)phenylacetic acid. After 20 – 30 min the patients generally are completely responsive .

Synthesis

Propanidid , propyl 3- methoxy-4-(N,N-diethylcarbamoylmethoxy)- phenylacetate, is a colorless to pale yellowish water-insoluble oil. It is prepared from the propyl ester of sodium homovanillic acid and N,N-diethylchloroacetamide .
Synthesis_1421-14-3

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 16)Suppliers
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Hubei Jusheng Technology Co.,Ltd.
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Career Henan Chemica Co
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Shaanxi Didu New Materials Co. Ltd
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TargetMol Chemicals Inc.
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55827 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Shanghai Bolu Biotechnology Co., Ltd 13062875887 13062875887 3662942976@QQ.com China 298 58
propanidid propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate PROPANIDIDE Bayer-1420 Epontol FBA-1420 Sombrevin TH-2180 WH-5668 2-[4-[2-(diethylamino)-2-keto-ethoxy]-3-methoxy-phenyl]acetic acid propyl ester propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate propyl 2-[4-[2-(diethylamino)-2-oxo-ethoxy]-3-methoxy-phenyl]ethanoate KEJXLQUPYHWCNM-UHFFFAOYSA-N Benzeneacetic acid, 4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-, propyl ester propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate USP/EP/BP BAY-1420 Fabantol Fabontal BAY-1420, Sombrevin propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate/Sombrevin 1421-14-3