zipeprol
- CAS No.
- 34758-83-3
- Chemical Name:
- zipeprol
- Synonyms
- zipeprol;Zipeprolum;Unii-G5muv8139h;Einecs 252-191-7;Zipeprol USP/EP/BP;Zipeprolum [inn-latin];34758-84-4 (Di-hydrochloride);α-(α-Methoxybenzyl)-4-(β-methoxyphenethyl)-1-piperazineethanol;1-Piperazineethanol, 4-(2-methoxy-2-phenylethyl)-α-(methoxyphenylmethyl)-;1-methoxy-3-(4-(2-methoxy-2-phenylethyl)piperazin-1-yl)-1-phenylpropan-2-ol
- CBNumber:
- CB0916495
- Molecular Formula:
- C23H32N2O3
- Molecular Weight:
- 384.52
- MDL Number:
- MOL File:
- 34758-83-3.mol
| Melting point | 83° |
|---|---|
| Boiling point | 507.7±50.0 °C(Predicted) |
| Density | 1.108±0.06 g/cm3(Predicted) |
| pka | 13.97±0.20(Predicted) |
| FDA UNII | G5MUV8139H |
| ATC code | R05DB15 |
zipeprol Chemical Properties,Uses,Production
Originator
Respilene,Winthrop,France,1973
Definition
ChEBI: Zipeprol is a benzyl ether.
Manufacturing Process
In a reactor provided with a mechanical stirrer, a reflux refrigerant and a
thermometer, there is introduced: 393 grams 1-[2-phenyl, 2-methoxy]ethyl
piperazine and 22 grams 3-phenyl-3-methoxy propylene oxide in 750 ml of
absolute ethanol.
When the slightly exothermic reaction (rise in temperature of about 20°C) has
ceased, heating is effected for 1.5 hours at 60°C. The product is then cooled
to 4°C and left to crystallize for about 12 hours. The precipitate is
centrifugated then recrystallized in 500 ml of absolute ethanol.
420 grams of the desired compound is thus obtained in the form of a white,
crystalline powder, melting point 83°C.
brand name
Antitaxil-z;Antituxil-z;Balutox;Broncozina;Bronx;Cerm-3024;Citizeta;Mirsol;Ogyline;Respilene;Respirase;Respirex;Santus;Talasa;Zitoxil.
Therapeutic Function
Bronchodilator