ChemicalBook >> CAS DataBase List >>ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE

ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE

CAS No.
107905-52-2
Chemical Name:
ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE
Synonyms
Ethyl 2-(2,2,2-Trifluoroethyl Phosphono)propionate;ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE;Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)propanoate;2-[Bis(2,2,2-trifluoroethoxy)phosphinyl]propanoic Acid Ethyl Ester;Propanoic acid, 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]-, ethyl ester
CBNumber:
CB1110483
Molecular Formula:
C9H13F6O5P
Molecular Weight:
346.16
MDL Number:
MFCD04039536
MOL File:
107905-52-2.mol
MSDS File:
SDS
Last updated:2024-05-06 11:31:08

ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE Properties

Boiling point 115-120°C/20mmHg
Density 1.381±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Oil
color Clear Colourless to Pale Yellow
CAS DataBase Reference 107905-52-2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H302-H335-H315
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HS Code  2931599090

ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E900050 Ethyl2-[Bis(2,2,2-trifluoroethyl)phosphono]Propionate 107905-52-2 100mg $120 2021-12-16 Buy
American Custom Chemicals Corporation OPC0000902 ETHYL-2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO]PROPIONATE 95.00% 107905-52-2 1G $739.2 2021-12-16 Buy
American Custom Chemicals Corporation OPC0000902 ETHYL-2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO]PROPIONATE 95.00% 107905-52-2 5G $960.75 2021-12-16 Buy
American Custom Chemicals Corporation OPC0000902 ETHYL-2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO]PROPIONATE 95.00% 107905-52-2 10G $2333.1 2021-12-16 Buy
Product number Packaging Price Buy
E900050 100mg $120 Buy
OPC0000902 1G $739.2 Buy
OPC0000902 5G $960.75 Buy
OPC0000902 10G $2333.1 Buy

ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE Chemical Properties,Uses,Production

Chemical Properties

Colourless Liquid

Uses

A wittig reagent.

Uses

Ethyl 2-[Bis(2,2,2-trifluoroethyl)phosphono] Propionate is an organic synthesis reagent, mainly used in organic synthesis and chemical production.

Synthesis

KHMDS (7.50 mL, 3.75 mmol, 0.5 M in toluene) was added to a solution of 18- crown-6 (4.10 g, 15.51 mmol), THF (20 mL), and bis (2,2,2-trifluoroethyl) phosphite (1) (0.50 mL, 3.41 mmol) by syringe in a dropwise manner at -78 ℃. Following 15 min, ethyl 2-bromopropionate (0.40 mL, 3.08 mmol) was added to the round bottom flask and the reaction mixture was allowed to stir for 4 hr at room temperature. Following the standard workup procedure, the crude product was then purified by flash column chromatography (3:1 to 2:1 hexanes:EtOAc, Rf = 0.33 in 1:1 hexanes:EtOAc) yielding Ethyl 2-[Bis(2,2,2-trifluoroethyl)phosphono] Propionate (112 mg, 0.33 mmol, 10.5%) as a yellow syrup.

107905-57-7
107905-52-2
Synthesis of ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE from Propanoic acid, 2-[bis[(trimethylsilyl)oxy]phosphinyl]-, ethyl ester

ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE Suppliers

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ETHYL 2-[BIS(2,2,2-TRIFLUOROETHYL)PHOSPHONO] PROPIONATE 2-[Bis(2,2,2-trifluoroethoxy)phosphinyl]propanoic Acid Ethyl Ester Ethyl 2-(2,2,2-Trifluoroethyl Phosphono)propionate Propanoic acid, 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]-, ethyl ester Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)propanoate 107905-52-2 C9H13F6O5P Wittig Reagents Miscellaneous Reagents