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4-dehydrowithaferin A

CAS No.
6850-30-2
Chemical Name:
4-dehydrowithaferin A
Synonyms
4-oxo Withaferin A;4-dehydrowithaferin A;Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-
CBNumber:
CB11316574
Molecular Formula:
C28H36O6
Molecular Weight:
468.58
MDL Number:
MOL File:
6850-30-2.mol
Last updated:2023-05-21 10:59:17

4-dehydrowithaferin A Properties

storage temp. Store at -20°C
solubility DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL
form A crystalline solid

4-dehydrowithaferin A price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28295 4-oxo Withaferin A 6850-30-2 1mg $87 2024-03-01 Buy
Cayman Chemical 28295 4-oxo Withaferin A 6850-30-2 5mg $304 2024-03-01 Buy
Cayman Chemical 28295 4-oxo Withaferin A 6850-30-2 10mg $478 2024-03-01 Buy
AK Scientific 1293CB 4-DehydrowithaferinA 6850-30-2 1mg $187 2021-12-16 Buy
Product number Packaging Price Buy
28295 1mg $87 Buy
28295 5mg $304 Buy
28295 10mg $478 Buy
1293CB 1mg $187 Buy

4-dehydrowithaferin A Chemical Properties,Uses,Production

Description

4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1 μM, respectively) and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.

References

1. Perestelo, N.R., Llanos, G.G., Reyes, C.P., et al. Expanding the chemical space of withaferin A by incorporating silicon to improve its clinical potential on human ovarian carcinoma cells J. Med. Chem. 62(9),4571-4585(2019).

4-dehydrowithaferin A Preparation Products And Raw materials

Raw materials

Preparation Products

4-dehydrowithaferin A Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
4-dehydrowithaferin A 4-oxo Withaferin A Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)- 6850-30-2