ChemicalBook >> CAS DataBase List >>4-dehydrowithaferin A
4-dehydrowithaferin A
- CAS No.
- 6850-30-2
- Chemical Name:
- 4-dehydrowithaferin A
- Synonyms
- 4-oxo Withaferin A;4-dehydrowithaferin A;Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-
- CBNumber:
- CB11316574
- Molecular Formula:
- C28H36O6
- Molecular Weight:
- 468.58
- MDL Number:
- MOL File:
- 6850-30-2.mol
Last updated:2023-05-21 10:59:17
4-dehydrowithaferin A price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 28295 | 4-oxo Withaferin A | 6850-30-2 | 1mg | $87 | 2024-03-01 | Buy |
Cayman Chemical | 28295 | 4-oxo Withaferin A | 6850-30-2 | 5mg | $304 | 2024-03-01 | Buy |
Cayman Chemical | 28295 | 4-oxo Withaferin A | 6850-30-2 | 10mg | $478 | 2024-03-01 | Buy |
AK Scientific | 1293CB | 4-DehydrowithaferinA | 6850-30-2 | 1mg | $187 | 2021-12-16 | Buy |
4-dehydrowithaferin A Chemical Properties,Uses,Production
Description
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1 μM, respectively) and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.
References
1. Perestelo, N.R., Llanos, G.G., Reyes, C.P., et al. Expanding the chemical space of withaferin A by incorporating silicon to improve its clinical potential on human ovarian carcinoma cells J. Med. Chem. 62(9),4571-4585(2019).
4-dehydrowithaferin A Preparation Products And Raw materials
Raw materials
Preparation Products
4-dehydrowithaferin A Suppliers
Global( 8)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7984 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |
4-dehydrowithaferin A
4-oxo Withaferin A
Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-22,27-dihydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-
6850-30-2