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Fluazinam

Fluazinam Structure
Fluazinam structure
CAS No.
79622-59-6
Chemical Name:
Fluazinam
Synonyms
Fluazinam Standard;3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)pyridin-2-amine;pp192;Mapro;B 1216;AltiMa;Sekoya;SHIRLAN;ikf1216;IKI 1216
CBNumber:
CB1161197
Molecular Formula:
C13H4Cl2F6N4O4
Molecular Weight:
465.09
MDL Number:
MFCD00214168
MOL File:
79622-59-6.mol
Last updated:2023-09-20 09:03:01
Request For Quotation

Fluazinam Properties

Melting point 100-102°
Boiling point 376.1±42.0 °C(Predicted)
Density 1.766±0.06 g/cm3(Predicted)
vapor pressure 1.5 x 10-3 Pa (25 °C)
Flash point 2 °C
storage temp. 2-8°C
solubility DMF:25.0(Max Conc. mg/mL);53.75(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);53.75(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);32.25(Max Conc. mM)
PBS (pH: 7.2):0.25(Max Conc. mg/mL);0.54(Max Conc. mM)
pka 7.11(at 25℃)
Water Solubility 1.7 mg l-1 (25 °C)
color Light yellow to Amber to Dark green
Merck 14,4117
BRN 4772672
InChIKey UZCGKGPEKUCDTF-UHFFFAOYSA-N
LogP 3.560
CAS DataBase Reference 79622-59-6(CAS DataBase Reference)
FDA UNII 0P91PCK33Q
Pesticides Freedom of Information Act (FOIA) Fluazinam
EPA Substance Registry System Fluazinam (79622-59-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H317-H318-H332-H361d-H410
Precautionary statements  P273-P280-P302+P352-P304+P340+P312-P305+P351+P338-P308+P313
Hazard Codes  T;N,N,T,Xn,F
Risk Statements  23-41-43-50/53-36-20/21/22-11-38-20-63
Safety Statements  26-36/37/39-45-60-61-36/37-16-63-57-56-38-28-27-24/25-20/21-13
RIDADR  UN 2811
WGK Germany  3
RTECS  UR8085000
HazardClass  6.1
PackingGroup  II
HS Code  29333990
NFPA 704
0
3 0

Fluazinam price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34095 Fluazinam PESTANAL , analytical standard 79622-59-6 100mg $133 2024-03-01 Buy
TCI Chemical F0869 Fluazinam >98.0%(HPLC)(T) 79622-59-6 1g $156 2024-03-01 Buy
TRC F407450 Fluazinam 79622-59-6 5g $1165 2021-12-16 Buy
American Custom Chemicals Corporation PST0000095 FLUAZINAM 95.00% 79622-59-6 5G $1859.55 2021-12-16 Buy
AK Scientific Q986 Fluazinam 79622-59-6 5g $396 2021-12-16 Buy
Product number Packaging Price Buy
34095 100mg $133 Buy
F0869 1g $156 Buy
F407450 5g $1165 Buy
PST0000095 5G $1859.55 Buy
Q986 5g $396 Buy

Fluazinam Chemical Properties,Uses,Production

Description

Fluazinam is a protective broad-spectrum contact fungicide registered for agricultural use to control various soil-borne fungal pathogens on a variety of crops, such as peanuts, potatoes, beans, etc. It can be applied as a foliar spray or soil treatment, which is effective against a number of diseases caused by pathogenic fungi such as gray mold, downy mildew, melanose, scab, alternaria blotch, clubroot, sclerotinia blight, white root rot, violet root rot. Besides, it shows acaricidal property, which can fight against mites in citrus.
However, as a protective agent, fluazinam is neither systemic or curative, which functions by inhibiting spore germination and spore growth, and also the development of infection structures, thereby giving it protective action with a good residual effect. The anti-fungal property of fluazinam acts by disrupting the energy production of the fungus at multiple sites and therefore preventing resistance.

Toxicology & Ecotoxicology

Rat LD50 (oral) :4,500 mg/kg (m), 4,100 mg/kg (f)
Rat LD50 (dermal) :> 2,000 mg/kg bw (m/f)
Rat LC50 (inhalation) :> 1.1 mg/L (m/f)
Skin irritation :mild irritant (rabbit)
Eye irritation :irritant (rabbit)
Skin sensitization :sensitizer (guinea pig)
Avian LD50 (acute oral) :> 4,190 mg/kg (mallard duck, m/f)
Avian LD50 (acute oral) :> 1,782 mg/kg (quail, m/f)
Fish LC50 :0.11 mg/L (rainbow trout, 96h)
Bee LD50 (oral) :> 100 μg/bee
Bee LD50 (contact) :> 100 μg/bee
Daphnia magna EC50 :0.19 mg/L (48 h)

Environmental Fate

Soil
Half-life- Aerobic = 132 days
Adsorption - Low mobility with Koc values ranged from 1705-2316
Persistence- Total fluazinam residues (fluazinam and its transformation products) are persistent in most environments and are likely to reach aquatic media through runoff. Fluazinam has the potential to bioaccumulate in fish.
Water
Half-life via hydrolysis - Stable at pH 5; 42 days at pH 7; and 6 days at pH 9
Surface water - Fluazinam and its transformation products are moderately persistent and may present concerns for transport to surface water by spray drift or runoff (especially in soils with low organic content)
Groundwater - Fluazinam should not leach substantially to groundwater.
Air
Volatilization- Fluazinam has a low vapor pressure 1.73 x 10-7 mm Hg and is not likely to substantially volatilize.
Degradates
Fluazinam may photolyze relatively rapidly in water (2.5 days) to form a tricyclic compound (G-504). Degradates were included in the drinking water risk assessment. The total fluazinam residues are persistent in most environments and are likely to reach aquatic media as a totality through runoff. The total residues may reach adjacent water bodies via runoff events and may be persistent.
Label use requirements are designed to mitigate related risk concerns

References

https://en.wikipedia.org/wiki/Fluazinam
http://www.agchemaccess.com/Fluazinam
http://www.galchimia.com/chemical-catalog/pesticide-impurities-and-metabolites/fluazinam-standard/
http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/325.htm

Description

Fluazinam, with a LogP of 3.56, has very low solubility in water (1.7 mgL?1, pH6.8, 25?C) but higher solubilities in organic solvents (e.g., acetone 470 g/L, dichloromethane 330 g/L, ethanol 150 g/L, all at 20 ?C). The active ingredient forms light yellow crystals with an MP of 115 to 117 ?C and has a vp of 1.5 mPa (25 ?C). The compound is stable to acid, alkali, and heat (5).

Chemical Properties

yellow crystal mp 115 ~ 117°C

Uses

Fluazinam is a broad spectrum fungicide. Fluazinam is commonly used for control of Sclerotinia blight and other soilborne pathogens of peanut as well for the control of potato blight.

Uses

Fluazinam is a fungicide with a protective action but with little curative or systemic activity. It is used to control grey mould and downy mildew on vines, apple scab, southern blight and white mould on peanuts and Phytophthora infestans and tuber blight on potatoes. It is also used against clubroot on crucifers, rhizomania on sugar beet and mites in apples.

Uses

Fluazinam, discovered and developed by ISK, is a highly active fungicide with broad spectrum activity, including soil borne diseases. Furthermore, it has acaricidal activity. Fluazinam is a multi-site contact fungicide that belongs to the pyridinamine family. Fluazinam has launched in several countries since its commercialization in the early 1990's. Now Fluazinam has established a strong presence in potato late blight, soybean white mold or turf fungicide market.

Definition

ChEBI: Fluazinam is a member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens. It has a role as an apoptosis inducer, an allergen, a xenobiotic, an environmental contaminant and an antifungal agrochemical. It is a C-nitro compound, a chloropyridine, an aminopyridine, a secondary amino compound, a member of monochlorobenzenes and a member of (trifluoromethyl)benzenes.

General Description

Fluazinam is a 2,6-dinitroaniline protectant fungicide, which belongs to the pyridinamine group. It can mostly find applications in agriculture.

Hazard

Moderately toxic by ingestion and inhalation. A reproductive hazard.

Agricultural Uses

Fungicide: Used to control Sclerotinia blight on peanuts and late blight and white mold on potatoes.

Trade name

FLUAZINAM 50 WP®; FROWNCIDE®; IKF-1216®; ICIA-192®; OMEGA; PP-192®; SHIRLAN®

Contact allergens

Fluazinam is a pesticide with a broad spectrum of anti fungal activity. It caused sensitization in employees in the tulip bulb industry and in farmers. Fluazinam induced contact dermatitis in a worker in a plant where it was manufactured.

Safety Profile

Moderately toxic by ingestion and inhalation. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx, F-, and Cl-.

Metabolic pathway

Fluazinam may typically be applied to crops of potatoes using up to 10 applications each of 150 g ha-1. Routes of degradation involve ring hydroxylation in aerobic soils and reduction of the nitro groups in flooded soils. A large amount of unextractable residue was observed. In potatoes and rats, important reactions involve the reduction of nitro groups and the formation of conjugates. In plants, the trifluoromethyl substituents are hydrolysed to carboxylic acid groups. Most of the information presented below was taken from an evaluation of the fungicide published by the UK Pesticide Safety Directorate (PSD, 1994).

Degradation

Fluazinam is stable to acid, alkali and heat (PM). The DT50 values for hydrolysis in buffer solutions held in the dark at 22 °C were 42 and 5.6 days at pH 7 and 9, respectively. There was no appreciable hydrolysis at pH 5. The major reaction involved hydrolysis of a trifluoromethyl group to give the nicotinic acid derivative (2). The DT50 values of fluazinam in buffer solutions exposed to natural sunlight were in the range 2-3 days. Up to 11 products were separated but only the major product formed at pH 9, the nicotinic acid derivative (2), was characterised (PED, 1994).

Fluazinam synthesis

29091-09-6
79456-26-1
79622-59-6
Synthesis of Fluazinam from 2,4-Dichloro-3,5-dinitrobenzotrifluoride and 3-Chloro-5-(trifluoromethyl)pyridin-2-amine

Fluazinam Preparation Products And Raw materials

Raw materials

3-Chloro-5-(trifluoromethyl)pyridin-2-amine

Preparation Products

Fluazinam Suppliers

Global( 239)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Junruifeng New Material Co.,Ltd.
+8613932838315 hsjkchemical@163.com CHINA 6 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd. 		+86-19930503282 alice@crovellbio.com China 8823 58
Supplier Advantage
Hebei Junruifeng New Material Co.,Ltd.
58
Hebei Mojin Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Hefei TNJ Chemical Industry Co.,Ltd. 		55
career henan chemical co 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Hebei Guanlang Biotechnology Co., Ltd. 		58

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View Lastest Price from Fluazinam manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fluazinam pictures 2023-08-18 Fluazinam
79622-59-6
 US $20.00 / KG 1KG 99% 50000kg Hebei Mojin Biotechnology Co., Ltd
Fluazinam pictures 2023-06-15 Fluazinam
79622-59-6
 US $71.00 / KG 1KG 99% 1000kg Baoji Guokang Bio-Technology Co., Ltd.
Fluazinam pictures 2023-02-16 Fluazinam
79622-59-6
 US $10.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
  • Fluazinam pictures
  • Fluazinam
    79622-59-6
  • US $20.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • Fluazinam pictures
  • Fluazinam
    79622-59-6
  • US $71.00 / KG
  • 99%
  • Baoji Guokang Bio-Technology Co., Ltd.
  • Fluazinam pictures
  • Fluazinam
    79622-59-6
  • US $10.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.

Fluazinam Spectrum

Fluazinam(79622-59-6)MSFluazinam(79622-59-6)1HNMRFluazinam(79622-59-6)13CNMRFluazinam(79622-59-6)IR1Fluazinam(79622-59-6)IR2

79622-59-6(Fluazinam)Related Search:

3,3',5,5'-Tetramethylbenzidine dihydrochloride N,N-Dimethylaniline PHENYL VALERATE Phenylhydrazine 2-Chloro-5-chloromethylpyridine
Epichlorohydrin N-Methyl-4-nitroaniline 4-Methylpyridine Chloroacetic acid 4-Chloro-2-nitroaniline
4-Nitroaniline 2-Nitroaniline Difluorochloromethane 5-CHLORO-4-METHYL-2-NITROANILINE 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE
2-Chloro-5-nitrobenzotrifluoride 2-Chloro-3,5-dinitrobenzotrifluoride 4-AMINO-2-CHLOROBENZOTRIFLUORIDE

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SHIRLAN FLUAZINAM ikf1216 pp192 shirlan(zeneca) shirlanflow 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluor-2,6-dinitro-p-toluidine 2-Pyridinamine, 3-chloro-N-3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl-5-(trifluoromethyl)- fluazinam (bsi,iso) fluaziname FLUAZINAM SOLUTION 3-Chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-dinitro-p-toluidine 3-Chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-dinitro-p-toluidine, 3-Chloro-N-(3-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridylamine 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifuor-2,6-dinitro-p-toluidine B 1216 IKI 1216 FROWNCIDE 3-chloro-n-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-2-pyridinamine 3-CHLORO-N-(3-CHLORO-2,6-DINITRO-4-TRIFLUOROMETHYLPHENYL)-5-TRIFLUOROMETHYL-2-PYRIDYLAMINE 3-CHLORO-N-(3-CHLORO-5-TRIFLUOROMETHYL-2-PYRIDYL)-ALPHA,ALPHA,ALPHA-TRIFLUORO-2,6-DINITRO-P-TOLUIDINE 3-chloro-n-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-2-pyridinamin 3-chloro-n-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-2-pyridinamin 6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-3-chloro-n-(5-chloro- asc66825 asc67178 Frowncide SC 3-Chloro-N-(5-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridinamine Fluazinam [iso] Hsdb 7264 Fluazinam 100mg [79622-59-6] AltiMa Mapro N-(3-Chloro-5-trifluoroMethyl-2-pyridyl)-2,6-dinitro-3-chloro-4-trifluoroMethylaniline Sekoya Fluazinam> Fluazinam @100 μg/mL in MeOH Altima(TM) 3-Chloro-N-(3-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridylamine, 3-Chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-dinitro-p-toluidine Fluazinam Solution, 1000ppm 3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-2-pyridina FluazinamSolution,100mg/L,5x1ml FluazinamSolution,100mg/L,1ml Fluazinam@1000 μg/mL in Methanol Fluazinam Standard 3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)pyridin-2-amine fluridine Fluazinam Solution in Methanol Fluazinam Solution in Acetonitrile 79622-59-6 9622-59-6 C13H4Cl2F6N4O4 C13H4CI2F6N4O4 API intermediates Agro-Products Amines Aromatics Heterocycles Intermediates & Fine Chemicals