ChemicalBook >> CAS DataBase List >>2,4-DIHYDROXY-6-METHYLBENZOIC ACID
2,4-DIHYDROXY-6-METHYLBENZOIC ACID
- CAS No.
- 480-64-8
- Chemical Name:
- 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
- Synonyms
- 133346;Orsellic acid;o-orsellinicaci;ORSELLINIC ACID;o-orsellinic acid;ORSELLINIC ACID MONOHYDRATE;2,4-DIHYDROXY-6-METHYLBENZOIC ACID;6-Methyl-2,4-dihydroxybenzoic acid;2-Methyl-4,6-dihydroxybenzoic acid;Benzoic acid, 2,4-dihydroxy-6-Methyl-
- CBNumber:
- CB1185500
- Molecular Formula:
- C8H8O4
- Molecular Weight:
- 168.15
- MDL Number:
- MFCD00210536
- MOL File:
- 480-64-8.mol
- MSDS File:
- SDS
Last updated:2024-03-29 18:52:01
| Melting point | 173-174°C |
|---|---|
| Boiling point | 257.07°C (rough estimate) |
| Density | 1.3037 (rough estimate) |
| refractive index | 1.5090 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | pK (25°) 3.90 |
| color | White to Pale Gray |
| Water Solubility | Soluble in water, dimethyl sulfoxide or 100% ethanol. |
| Stability | Hygroscopic |
| CAS DataBase Reference | 480-64-8 |
| FDA UNII | 11XLA0494B |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| NFPA 704 |
|
2,4-DIHYDROXY-6-METHYLBENZOIC ACID price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22708 | Orsellinic Acid ≥98% | 480-64-8 | 10mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 22708 | Orsellinic Acid ≥98% | 480-64-8 | 50mg | $225 | 2024-03-01 | Buy |
| Cayman Chemical | 22708 | Orsellinic Acid ≥98% | 480-64-8 | 100mg | $337 | 2024-03-01 | Buy |
| Cayman Chemical | 22708 | Orsellinic Acid ≥98% | 480-64-8 | 250mg | $632 | 2024-03-01 | Buy |
| Usbiological | 461634 | Orsellinic Acid | 480-64-8 | 1mg | $403 | 2021-12-16 | Buy |
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Chemical Properties,Uses,Production
Description
Orsellinic acid is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an IC50 value of 5 mM. Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (Pafr-/-) mouse cerebellar granule cells.
Uses
Orsellinic acid is a benzoic acid compound shown to block PAF-mediated neuronal apoptosis.
Definition
ChEBI: A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group.
Biosynthesis
One of the simplest polyketide derivatives, orsellinic acid is widely distributed in fungi. It is biosynthesised from an acetate starter unit and three malonyl units, as shown in Figure. Intramolecular condensation of the polyketide chain gives orsellinic acid without further modification.
The biosynthesis of orsellinic acid.
Synthesis Reference(s)
The Journal of Organic Chemistry, 30, p. 3566, 1965 DOI: 10.1021/jo01021a507
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Suppliers
Global( 117)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7845 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 12755 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Taizhou Blazer Biomedical Technology Co., Ltd. | 0523-86112008 13915404123 | sales@blazerbio.com | China | 88 | 58 |
View Lastest Price from 2,4-DIHYDROXY-6-METHYLBENZOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-29 | 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
480-64-8
|
US $8.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2020-01-09 | 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
480-64-8
|
US $3.00 / KG | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
480-64-8
- US $8.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
480-64-8
- US $3.00 / KG
- 98%
- Career Henan Chemical Co
480-64-8(2,4-DIHYDROXY-6-METHYLBENZOIC ACID)Related Search:
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ETHYL 3,5-DIBROMO-2,4-DIHYDROXY-6-METHYLBENZOATE
FUMARPROTOCETRARIC ACID
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METHYL 2,4-DIMETHOXY-6-METHYLBENZOATE
EVERNIC ACID
1of4
2,4-DIHYDROXY-6-METHYLBENZOIC ACID
ORSELLINIC ACID
ORSELLINIC ACID MONOHYDRATE
2,4-Dihydroxy-6-methylbenzoic acid hydrate, 97%
2-Methyl-4,6-dihydroxybenzoic acid
6-Methyl-2,4-dihydroxybenzoic acid
Orsellic acid
o-orsellinic acid
Benzoic acid, 2,4-dihydroxy-6-Methyl-
133346
o-orsellinicaci
480-64-8
Inhibitors
Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts