Zearalenone
- CAS No.
- 17924-92-4
- Chemical Name:
- Zearalenone
- Synonyms
- ZEN;ZON;(s)-zearalenone;RAL;(-)-Zearalenone;[S-(E)]-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione;ZENONE;toxinf2;f-2toxin;(3S,11E)-
- CBNumber:
- CB4131407
- Molecular Formula:
- C18H22O5
- Molecular Weight:
- 318.36
- MDL Number:
- MFCD00133085
- MOL File:
- 17924-92-4.mol
- MSDS File:
- SDS
| Melting point | 164-165°C |
|---|---|
| alpha | 25546 -170.5° (c = 1.0 in CH3OH) |
| Boiling point | 377.53°C (rough estimate) |
| Density | 1.1270 (rough estimate) |
| refractive index | 1.6120 (estimate) |
| Flash point | 6 °C |
| storage temp. | 2-8°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml; Ethanol: 20 mg/ml |
| pka | 7.58±0.40(Predicted) |
| color | Off-white |
| Merck | 13,10169 |
| BRN | 1350216 |
| InChIKey | MBMQEIFVQACCCH-QBODLPLBSA-N |
| LogP | 3.830 (est) |
| CAS DataBase Reference | 17924-92-4(CAS DataBase Reference) |
| FDA UNII | 5W827M159J |
| EPA Substance Registry System | Zearalenone (17924-92-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H361d | |||||||||
| Precautionary statements | P202-P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | C,Xn,F | |||||||||
| Risk Statements | 34-62-63-36-20/21/22-11 | |||||||||
| Safety Statements | 26-36/37/39-45-36-16-36/37 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DM2550000 | |||||||||
| F | 10 | |||||||||
| HS Code | 29322090 | |||||||||
| NFPA 704 |
|
Zearalenone price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CRM46916 | Zearalenone solution certified reference material, 50?μg/mL in acetonitrile, ampule of 1?mL | 17924-92-4 | 1mL | $111 | 2024-03-01 | Buy |
| Sigma-Aldrich | 34126 | Zearalenone solution 100 μg/mL in acetonitrile, analytical standard | 17924-92-4 | 2ml | $488 | 2024-03-01 | Buy |
| Sigma-Aldrich | 32939 | Zearalenone reference material | 17924-92-4 | 5mg | $689 | 2022-05-15 | Buy |
| Cayman Chemical | 11353 | Zearalenone ≥98% | 17924-92-4 | 5mg | $39 | 2024-03-01 | Buy |
| Cayman Chemical | 11353 | Zearalenone ≥98% | 17924-92-4 | 10mg | $73 | 2024-03-01 | Buy |
Zearalenone Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
A phytoestrogenic mycotoxin and ER activator
Uses
Estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. One of a group of compounds known as resorcylic acid lactones
Uses
Zearalenone is a resorcylic acid lactone produced by a number of Fusarium sp.. Zearalenone acts as a non-steroidal estrogen, binding to estrogen receptor and is uterotropic. Zearalenone induces reproductive problems in animals and, in some animal models, is thought to be a primary initiator of hepatic tumours. In vivo, zearalenone undergoes metabolic reduction to the more estrogenic zearalenol. Contamination of grains, notably maize, by Fusarium species gives rise to high levels of zearalenone and is regarded as an important food quality issue for both humans and animal health.
Definition
ChEBI: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
General Description
White microcrystals or white powder.
Air & Water Reactions
Zearalenone may be sensitive to prolonged exposure to air. Insoluble in water.
Reactivity Profile
Zearalenone is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Zearalenone may be incompatible with alkalis.
Fire Hazard
Flash point data for Zearalenone are not available. Zearalenone is probably combustible.
Biochem/physiol Actions
Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.
Metabolic pathway
When zearalenone is subjected to microbial transformation by a fungus, Gliocladium roseum, it is converted to a 1 : 1 mixture of 1-(3,5-dihydroxyphenyl)- 10 0 -hydroxy-1-undecen-6'-one and 1-(3,5- dihydroxyphenyl)-6'-hydroxy-1-undecen-10'-one.
storage
-20°C
Zearalenone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Zearalenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-26 | Zearalenone
17924-92-4
|
US $0.00-0.00 / KG | 100g | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | Zearalenone
17924-92-4
|
US $1.00 / kg | 1kg | 95%-99% | 1000kg | Career Henan Chemical Co |
-
- Zearalenone
17924-92-4
- US $0.00-0.00 / KG
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- Zearalenone
17924-92-4
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co