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R-IMPP

R-IMPP structure

CAS No.: 2133832-83-2

Chemical Name:: R-IMPP

Synonyms: R-IMPP;PF-00932239 (R-IMPP);Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases

CBNumber:: CB13155117

Molecular Formula:: C24H27N3O2

Molecular Weight:: 389.49

MDL Number:: MFCD31544323

MOL File:: 2133832-83-2.mol

Last updated:2023-05-21 10:59:17

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R-IMPP Properties

Boiling point	594.4±50.0 °C(Predicted)
Density	1.186±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 1 mg/ml; DMSO: 10 mg/ml
form	A crystalline solid
pka	9.14±0.10(Predicted)

R-IMPP price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	20861	(R)-IMPP	2133832-83-2	1mg	$73	2024-03-01	Buy
Cayman Chemical	20861	(R)-IMPP	2133832-83-2	25mg	$1075	2024-03-01	Buy
Cayman Chemical	20861	(R)-IMPP	2133832-83-2	5mg	$288	2024-03-01	Buy
Cayman Chemical	20861	(R)-IMPP	2133832-83-2	10mg	$539	2024-03-01	Buy
ChemScene	CS-7579	R-IMPP 99.36%	2133832-83-2	50mg	$680	2021-12-16	Buy

Product number	Packaging	Price	Buy
20861	1mg	$73	Buy
20861	25mg	$1075	Buy
20861	5mg	$288	Buy
20861	10mg	$539	Buy
CS-7579	50mg	$680	Buy

R-IMPP Chemical Properties,Uses,Production

Description

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC₅₀ = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.

R-IMPP Preparation Products And Raw materials

Raw materials

Preparation Products

R-IMPP Suppliers

Global( 31)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33350	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3445	55
Medi-tech Bioscientific Co., Ltd.	0519-83246372 13585352506		China	1844	58
Angel Pharmatech, Ltd.	17317130613	3358272972@qq.com	China	3242	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
InvivoChem	58
TargetMol Chemicals Inc.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
MedChemexpress LLC	58
Shanghai EFE Biological Technology Co., Ltd.	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Medi-tech Bioscientific Co., Ltd.	58
Angel Pharmatech, Ltd.	58

R-IMPP Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl- PF-00932239 (R-IMPP) (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases 2133832-83-2