R-IMPP

R-IMPP Struktur
2133832-83-2
CAS-Nr.
2133832-83-2
Englisch Name:
R-IMPP
Synonyma:
R-IMPP;PF-00932239 (R-IMPP);Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
CBNumber:
CB13155117
Summenformel:
C24H27N3O2
Molgewicht:
389.49
MOL-Datei:
2133832-83-2.mol

R-IMPP Eigenschaften

Siedepunkt:
594.4±50.0 °C(Predicted)
Dichte
1.186±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMF: 1 mg/ml; DMSO: 10 mg/ml
Aggregatzustand
A crystalline solid
pka
9.14±0.10(Predicted)

Sicherheit

R-IMPP Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.

R-IMPP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


R-IMPP Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 31)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32715 60
InvivoChem
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TargetMol Chemicals Inc.
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Shanghai Acmec Biochemical Technology Co., Ltd.
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Aladdin Scientific
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MedChemexpress LLC 021-58955995
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9709 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
klq@cw-bio.com China 3500 55
Medi-tech Bioscientific Co., Ltd. 0519-83246372 13585352506
China 1844 58
Angel Pharmatech, Ltd. 17317130613
3358272972@qq.com China 3245 58

  • R-IMPP
  • Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-
  • PF-00932239 (R-IMPP)
  • (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide
  • Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
  • 2133832-83-2
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