5-THIO-D-GLUCOSE
- CAS No.
- 20408-97-3
- Chemical Name:
- 5-THIO-D-GLUCOSE
- Synonyms
- d-glucos;NSC 204984;THIOGLUCOSE;5-Thioglucose;5-THIO-D-GLUCOSE;GLUCOTHIOPYRANOSE;D-Glucose, 5-thio-;α-D-Glucothiopyranose;5-Thio-D-glucose ,98%;5-Thio-α-D-glucopyranose
- CBNumber:
- CB1358757
- Molecular Formula:
- C6H12O5S
- Molecular Weight:
- 196.22
- MDL Number:
- MFCD00148892
- MOL File:
- 20408-97-3.mol
| Melting point | 135-138 °C(lit.) |
|---|---|
| Boiling point | 303.11°C (rough estimate) |
| Density | 1.271 (estimate) |
| refractive index | 1.5060 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in Water (up to 15 mg/ml) |
| pka | 9.11±0.10(Predicted) |
| form | Powder |
| color | White |
| optical activity | [α]/D 220.0±5.0°, c = 1 in 0.1 M HCl |
| Water Solubility | Miscible with water. |
| Merck | 13,9408 |
| BRN | 1865193 |
| Stability | Stable for 2 years as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months. |
| CAS DataBase Reference | 20408-97-3 |
| FDA UNII | 3PRV1384UO |
| EPA Substance Registry System | D-Glucose, 5-thio- (20408-97-3) |
5-THIO-D-GLUCOSE price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 88635 | 5-Thio-D-glucose ≥98.0% (HPLC) | 20408-97-3 | 1g | $1750 | 2024-03-01 | Buy |
| Alfa Aesar | J63621 | 5-Thio-D-glucose, 97+% | 20408-97-3 | 25mg | $181 | 2023-06-20 | Buy |
| TRC | T350725 | 5-Thio-D-glucose | 20408-97-3 | 0.5mg | $165 | 2021-12-16 | Buy |
| Usbiological | 294755 | 5-Thio-D-glucose | 20408-97-3 | 25mg | $340 | 2021-12-16 | Buy |
| Usbiological | 161986 | 5-Thio-D-glucose | 20408-97-3 | 10mg | $425 | 2021-12-16 | Buy |
5-THIO-D-GLUCOSE Chemical Properties,Uses,Production
Description
5-Thio-D-glucose (20408-97-3) is a potent competitive inhibitor of the cellular transport of glucose and glucose-mediated insulin release.1 May be used to induce a state of glucose deprivation in laboratory animals.2 Stimulates feeding in rat models.3? Induces Alzheimer-like changes in frontal cortex and hippocampus in rats.4? Elevates renal TGF-b1 at a dose that does not prevent streptozotocin diabetes in rats.5
Uses
5-Thio-D-glucose (cas# 20408-97-3) is a compound useful in organic synthesis.
References
Wang et al. (1995) Glucose transporter 2 expression: prevention of streptozotocin-induced reduction in beta-cells with 5-thio-D-glucose; Clin. Endocrinol. Diabetes, 103 83 Suppl.2 Shah et al. (2019), Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus; J. Physiol. Endocrinol. Metab., 316 E948 Li et al. (2014), Stimulation of feeding by three different glucose-sensing mechanisms requires hindbrain catecholamine neurons; J. Physiol. Regul. Integr. Comp. Physiol., 306 R257 Salkovic-Petrisic et al. (2006), Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signaling pathway; J. Neurochem., 96 1005 Lane et al. (2000), 5-thio-D-glucose elevates renal transforming growth factor beta-1 at a dose that does not prevent streptozotocin diabetes in rats; Endocrinology, 141 3337
5-THIO-D-GLUCOSE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7019 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29067 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5989 | 58 |
View Lastest Price from 5-THIO-D-GLUCOSE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-16 | 5-Thio-D-glucose
20408-97-3
|
US $0.00 / G | 10G | 98%min | 30kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2019-07-06 | 5-THIO-D-GLUCOSE
20408-97-3
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
-
- 5-Thio-D-glucose
20408-97-3
- US $0.00 / G
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 5-THIO-D-GLUCOSE
20408-97-3
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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