2,6-Dichloropurine
- CAS No.
- 5451-40-1
- Chemical Name:
- 2,6-Dichloropurine
- Synonyms
- 2,6-DICHLORO-9H-PURINE;2,6-dichloro-7H-purine;2,6-dichloro-1H-purine;NSC 18395;Dichloropurine;6-Dichloropurine;2,6-DICHLOROPURINE;2,6-Dichloropurine>Cefepime Intermediate;2,6-Dichloropurine.97%
- CBNumber:
- CB1720642
- Molecular Formula:
- C5H2Cl2N4
- Molecular Weight:
- 189
- MDL Number:
- MFCD09749894
- MOL File:
- 5451-40-1.mol
- MSDS File:
- SDS
Melting point | 185-195 °C (dec.) (lit.) |
---|---|
Boiling point | 310.62°C (rough estimate) |
Density | 1.7265 (rough estimate) |
refractive index | 1.6300 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | soluble |
pka | 5.22±0.20(Predicted) |
form | Crystalline Powder |
color | White to yellow |
Water Solubility | soluble |
BRN | 9354 |
InChIKey | RMFWVOLULURGJI-UHFFFAOYSA-N |
CAS DataBase Reference | 5451-40-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H301 | |||||||||
Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 36/37/38-22 | |||||||||
Safety Statements | 22-24/25-37/39-26-36 | |||||||||
RIDADR | UN2811 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
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2,6-Dichloropurine price More Price(39)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D73103 | 2,6-Dichloropurine 97% | 5451-40-1 | 1g | $17.48 | 2024-03-01 | Buy |
Sigma-Aldrich | D73103 | 2,6-Dichloropurine 97% | 5451-40-1 | 5g | $83.2 | 2024-03-01 | Buy |
TCI Chemical | D2470 | 2,6-Dichloropurine >97.0%(HPLC)(T) | 5451-40-1 | 1g | $24 | 2024-03-01 | Buy |
TCI Chemical | D2470 | 2,6-Dichloropurine >97.0%(HPLC)(T) | 5451-40-1 | 5g | $60 | 2024-03-01 | Buy |
Alfa Aesar | B21289 | 2,6-Dichloropurine, 97% | 5451-40-1 | 1g | $76.65 | 2024-03-01 | Buy |
2,6-Dichloropurine Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
2,6-Dichloropurine is used in the synthesis of 2,6-diamino-substituted purine derivatives as potential cardiomyogenesis inducing agents.
Uses
Suzuki-Miyaura cross-coupling between halopurines and arylboronic acids in water-acetonitrile.1
Synthesis Reference(s)
Journal of the American Chemical Society, 80, p. 404, 1958 DOI: 10.1021/ja01535a040
Purification Methods
It can be recrystallised from 150 parts of boiling H2O and dried at 100o to constant weight. It is soluble in EtOAc. The HgCl2 salt separates from EtOH solution. UV: max 275nm ( 8.9K) at pH 1; and 280nm ( 8.5K) at pH 11 [Elion & Hitchings J Am Chem Soc 78 3508 1956, Schaeffer & Thomas J Am Chem Soc 80 3738 1958, Beaman & Robins J Appl Chem (London) 12 432 1962, Montgomery J Am Chem Soc 78 1928 1956]. [Beilstein 26 III/IV 1747.]
2,6-Dichloropurine Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 | wucy@ribio.com.cn | China | 117 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5987 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Chongqing Zhihe Biopharmaceutical Co., Ltd. | +8618580541567 | sales@zhswyy.com | China | 303 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20291 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615383190639 | admin@86-ss.com | China | 1000 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
View Lastest Price from 2,6-Dichloropurine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-24 | 2,6-Dichloropurine
5451-40-1
|
US $100.00-75.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
2024-09-23 | 2,6-Dichloropurine
5451-40-1
|
US $0.00-0.00 / g | 1g | 99.99% | 20 tons | airuikechemical co., ltd. | ||
2024-09-19 | 2,6-Dichloropurine
5451-40-1
|
US $0.00-0.00 / kg | 0.10000000149011612kg | 99 | 20tons | Chongqing Zhihe Biopharmaceutical Co., Ltd. |
- 2,6-Dichloropurine
5451-40-1
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
- 2,6-Dichloropurine
5451-40-1
- US $0.00-0.00 / g
- 99.99%
- airuikechemical co., ltd.
- 2,6-Dichloropurine
5451-40-1
- US $0.00-0.00 / kg
- 99
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
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