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ChemicalBook >> CAS DataBase List >>N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine

N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine

N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Structure
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine structure
CAS No.
30414-15-4
Chemical Name:
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine
Synonyms
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine;L-Serine, N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)-L-seryl]-
CBNumber:
CB18571035
Molecular Formula:
C20H20N2O11
Molecular Weight:
464.38
MDL Number:
MOL File:
30414-15-4.mol
Last updated:2023-04-23 13:52:06
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N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Properties

Boiling point 869.4±65.0 °C(Predicted)
Density 1.617±0.06 g/cm3(Predicted)
form A solid
pka 3.06±0.10(Predicted)

N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Chemical Properties,Uses,Production

Description

N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine is a microbial metabolite and degradation product of the bacterial siderophore enterobactin that has been found in Streptomyces and has anticancer activity.1,2,3 It inhibits invasion of 26-L5 murine colon cancer cells in a Matrigel? assay with an IC50 value of 2.7 μM.1

References

1. Igarashi, Y., Iida, T., Fukuda, T., et al. Catechoserine, a new catecholate-type inhibitor of tumor cell invasion from Streptomyces sp J. Antibiot. (Tokyo) 65(4),207-209(2012).
2. O'Brien, I.G., Cox, G.B., and Gibson, F. Enterochelin hydrolysis and iron metabolism in Escherichia coli Biochim. Biophys. Acta 237(3),537-549(1971).
3. Raines, D.J., Moroz, O.V., Blagova, E.V., et al. Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product Proc. Natl. Acad. Sci. USA 113(21),5850-5855(2016).

N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Preparation Products And Raw materials

Raw materials

Preparation Products

N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
Supplier Advantage
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
ChemeGen 中国 58
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine L-Serine, N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)-L-seryl]- 30414-15-4