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N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine

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Company Name: BOC Sciences  
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Products Intro: Product Name:N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine
CAS:30414-15-4
Purity:>95% by HPLC Remarks:0
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
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Products Intro: Product Name:N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine
CAS:30414-15-4
Purity:95% Package:100μg;500μg
Company Name: ChemeGen 中国  
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Products Intro: Product Name:N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine
CAS:30414-15-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: Cayman Chemical Company  
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Products Intro: Product Name:N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine
CAS:30414-15-4
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Basic information
Product Name:N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine
Synonyms:N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine;L-Serine, N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)-L-seryl]-
CAS:30414-15-4
MF:C20H20N2O11
MW:464.38
EINECS:
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Mol File:30414-15-4.mol
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Structure
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Chemical Properties
Boiling point 869.4±65.0 °C(Predicted)
density 1.617±0.06 g/cm3(Predicted)
form A solid
pka3.06±0.10(Predicted)
Safety Information
MSDS Information
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Usage And Synthesis
DescriptionN,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine is a microbial metabolite and degradation product of the bacterial siderophore enterobactin that has been found in Streptomyces and has anticancer activity.1,2,3 It inhibits invasion of 26-L5 murine colon cancer cells in a Matrigel? assay with an IC50 value of 2.7 μM.1
References1. Igarashi, Y., Iida, T., Fukuda, T., et al. Catechoserine, a new catecholate-type inhibitor of tumor cell invasion from Streptomyces sp J. Antibiot. (Tokyo) 65(4),207-209(2012).
2. O'Brien, I.G., Cox, G.B., and Gibson, F. Enterochelin hydrolysis and iron metabolism in Escherichia coli Biochim. Biophys. Acta 237(3),537-549(1971).
3. Raines, D.J., Moroz, O.V., Blagova, E.V., et al. Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product Proc. Natl. Acad. Sci. USA 113(21),5850-5855(2016).
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Preparation Products And Raw materials
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